Patents Represented by Attorney Novartis Vaccines & Diagnostics SRL

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  • Cytotoxic T-cell epitopes from
    Patent number: 7754228
    Abstract: Cytotoxic T-cell epitopes from C.pneumoniae proteins have been empirically determined. The epitopes from corresponding C.trachomatis proteins have also been identified, and some of these are identical to those from C.pneumoniae. The empirical method showed that algorithmic prediction was inadequate. The epitopes are useful for immunisation and/or diagnosis.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: July 13, 2010
    Assignee: Novartis Vaccines and Diagnostics, Srl
    Inventors: Giuliano Bensi, Guido Grandi, Sergio Abrignani
  • Non-toxic mucosal adjuvant
    Patent number: 7485304
    Abstract: A non-toxic mucosal adjuvant is provided which may be admixed with further antigens to provide a vaccine administrable to mucosal surfaces in organisms including man. Preferably, the non-toxic mucosal adjuvant is a detoxified mutant of a bacterial ADP-ribosylating toxin, optionally comprising one or more amino acid additions, deletions or substitutions.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: February 3, 2009
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventor: Rino Rappuoli