Abstract: For evaluation of a target DNA sequence, a sample mixture is prepared containing one or more sets of sequencing polynucleotide fragments, each set containing fragments having lengths indicative of the positions of at least one base within the target DNA sequence. These sequencing fragment sets are each labeled with a different type of label (for example fluorescent labels). The sample mixture also includes a set of calibrant polynucleotide fragments having a plurality of known fragment lengths. The calibrant polynucleotide fragments are labeled with a spectroscopically-distinguishable calibrant label. The sample mixture is then electrophoretically separated to separate the polynucleotide fragments as a function of fragment length. Real-time detection is used to detect the label(s) on the set(s) of sequencing fragments and the calibrant label as they migrate in a common lane of the separation medium to produce a sequencing data trace and a calibrant data trace.

Abstract: The present invention relates to the use of a sex pheromone, E8,E10-dodecadien-1-ol, in combination with one or more behavioral antagonists or behavioral synergists for control of codling moth by mating disruption or attraction & killing.

Abstract: A passively mode-locked solid-state laser for emitting a continuous-wave train of electromagnetic-radiation pulses, the fundamental repetition rate of the emitted pulses exceeding 1 GHz, without Q-switching has an optical resonator, a solid-state laser gain element placed inside the optical resonator, an exciter for exciting said laser gain element to emit electromagnetic radiation having the effective wavelength, and a saturable absorber for passive mode locking. The laser gain element preferably consists of a laser material with a stimulated emission cross section exceeding 0.8×10−18 cm−2 at the effective wavelength. Typically, the laser gain element is made of Nd:vanadate. The saturable absorber is preferably a semiconductor saturable absorber mirror device. The laser is simple, robust, compact, efficient, and low-cost.

Abstract: The invention relates to method and apparatus for the hyper-rapid freezing of liquid samples. The samples are converted into droplets or vapor and rapidly driven directly onto the surface of a solid or slushed refrigerant.

Abstract: For conveying individually held products (3) in a network of conveying paths (A, B), a holding element (4) is associated with each product (3) and is conveyed together with the product along the entire conveying route for the product (3) which route contains various conveying paths (A, B). Each holding element (4) comprises at least one first coupling part (1) for being coupled to a conveying element being movable along a given conveying path (A, B) and comprising a second coupling parts (2) or for being coupled to guides extending along the conveying paths. In transfer areas (U) in which products and holding means are transferred from one conveying path to another conveying path control means are provided for uncoupling holding elements (4) from conveying elements or guides of a first conveying path (A) and for coupling holding elements (4) to conveying elements or guides of a second conveying path (B).

Abstract: An apparatus for injection molding or forming of work pieces, including closed profile work pieces, is provided that is less expensive and requires less space than known press apparatus. The apparatus locks a molding tool assembled from two or more tool pieces to define the shape of a molded or formed product using a frame, and one or more presses. The frame defines an interior space extending from a first end of the frame to an opposed second end of the frame for receiving a molding tool. The presses are placed within the frame and act in concert with the frame to apply pressure to a molding tool. The interior space is large enough to receive an assembled molding tool into the interior space of the frame, while not permitting removal of the tool pieces from the product within the interior space.

Abstract: The 4-pass amplifier comprises an optical isolator (7), a polarizing beamsplitter (2), a gain material (3) and a first and a second reflecting element (5, 6). It further comprises means (4) for modifying the polarization state of a light beam after passing through said gain material for a first time and before passing through said gain material for a second time with respect to two orthogonal axes in a way which is equivalent to exchanging said two orthogonal axes. The polarization-rotating means (4) rotate the polarization of the light by 45° and are preferably a Faraday rotator. The reflecting element (5) is, e.g., a multilayer dielectric mirror. An incident light beam (1) is linearly polarized by the polarizing beamsplitter (2), amplified by the gain material (3), its polarization plane is rotated by the polarization rotator (4) by 45°, and the light beam is reflected by the reflecting element (5). It passes again through the polarization rotator (4) and the gain material (3).

Abstract: A sub-nanosecond passively Q-switched microchip laser is disclosed. It combines an optically pumped, passively Q-switched, high-frequency, microchip laser producing short pulses with an optically end-pumped amplifier producing high small-signal gain while pumped at low power. The microchip laser for emitting pulsed laser radiation is a monolithic body comprising two reflective elements defining an optical resonator for laser radiation, a laser gain medium, e.g., Nd:YAG, and a saturable absorber medium, e.g., Cr4+:YAG placed inside said resonator. The optical amplifier stage for amplifying the laser radiation comprises an amplifying medium, e.g., Nd:YVO4. The microchip laser and the amplifier are optically end-pumped, preferably by high-brightness diodes. This entirely passive laser system directly produces &mgr;J pulses at repetition rates of about 45 kHz.

Abstract: Injection of even very small amounts of supplemental water to the spent-air stream at points upstream from the heat exchanger cooler(s) used in processing spent-air streams from a cumene-to-phenol process allows these heat exchanger coolers to act as both extractors and condensers. It is therefore possible to recover from the heat exchanger cooler a methanol/water condensate, thereby substantially reducing the amount of methanol in the spent-air stream prior to discharge. Thus, known methods for manufacture of phenol from cumene in which an oxygen-containing gas stream is passed through liquid cumene to produce an oxidate product and a spent-air stream comprising methanol and cumene and a saturating amount of water; and in which the spent-air stream is passed through one or more heat exchanger coolers and a carbon bed prior to discharge can be improved.

Abstract: The present invention refers to an arrangement for transferring data through a computer network including at least one transmitting client and one receiving client, said data being arranged in an E-mail, specially a HTML E-mail. The arrangement further comprises a server unit including means to store managing programmes. The E-mail further including at least one attachment information, including a pointer to said server and said managing programmes for executing and processing said attachment information.

Abstract: A fully packaged current monitor system for galvanically isolated current measurement is manufactured in line with commercial IC fabrication and LOC packaging technology. A current path is part of the lead frame on which a die with sensor means is mounted with the aid of an electrically insulating correspondingly pre-patterned glue tape, the structured surface of the die facing the lead frame. The system manufactured in this way achieves for currents up to +/−10 A, a system accuracy of better than 50 mA and is applicable for currents up to the order of 50 A. The system performance can be further improved by ferromagnetic field concentrators and on-chip compensation techniques.

Abstract: Improved fire-retarded properties can be imparted to polycarbonate resin composition by incorporating into the polycarbonate a fire-retardant component containing a perfluoroallkane sulfonate such as potassium perfluorobutane sulfonate and a cyclic siloxane such as octaphenylcyclotetrasiloxane. The fire-retardant component is suitably added at levels to form a polycarbonate composition in which the perfluoroalkane sulfonate is present in an amount of from 0.02 to 0.1 phr relative to the composition as a whole, and the cyclic siloxane is present in an amount of at least 0.02 relative to the composition as a whole.

Abstract: A process is given for permitting the application to a substrate (2) of a microsystem or transducer (1) having a first partial surface (13), whose interaction with the environment is to be possible, and a second partial surface (14), which is to be protected against external influences. The substrate (2) is prepared, a passage point (20) being produced in said substrate (2). The microsystem (1) and substrate (2) are so mutually positioned that the first partial surface (13) faces the substrate (2) and that the passage point (20) in the substrate (2) and the first partial surface (13) come to rest opposite one another. Contacts (50, 51.1, 51.2) are produced by flip-chip technology. A sealing contact (51.1, 51.2) seals the second partial surface (14) against external influences. A gap (3) between the microsystem (1) and substrate (2) is filled with a filling material (30). A selective cover (24) over the passage point (20) keeps undesired external influences away from the first partial surface (13).

Abstract: Tolerance of the immune system for self differentiation antigens can be overcome and an immune response stimulated by administration of a therapeutic differentiation antigen. The therapeutic differentiation antigen is altered with respect to the target differentiation antigen in the individual being treated (i.e., the differentiation antigen to which an immune response is desired) in one of three ways. First, the therapeutic differentiation antigen may be syngeneic with the target differentiation antigen, provided that therapeutic differentiation antigen is expressed in cells of a species different from the individual being treated. For example, a human differentiation antigen expressed in insect or other non-human host cells can be used to stimulate an immune response to the differentiation antigen in a human subject. Second, the therapeutic differentiation antigen may be a mutant form of a syngeneic differentiation antigen, for example a glycosylation mutant.

Abstract: Preliminary clinical studies in humans have now been done which show both the efficacy of 10-propargyl-10dAM and a preferred dosage schedule for such treatments. In addition, it has now been determined that combinations of 10-propargyl-10-deazaaminopterin (preferably highly purified forms, substantially free of 10-deazaaminopterin) with taxols exhibit synergistic effectiveness in the treatment of tumors. 10-propargyl-10-deazaaminopterin and a taxol in therapeutically effective amounts can be administered concurrently, one right after the other, or with a period of time in between.

Abstract: A transverse rf saddle coil (30) for use in NMR is affixed in intimate thermal conract on one surface of a ceramic coilform (23) of high thermal conductivity. The probe is mostly for use with solid samples at high fields where the axis of the coilform is not alignedwith the main field. An orthogonal rf coil (1) is mounted in intimate thermal contact to the first saddle coil (30) via a ceramic spacer or coilform (2). The coilform is cooled by high-velocity gas flow and is also often associated with bearing exhaust gas from a high speed sample spinner. The two coils are tuned to different rf frequencies with circuits capable of supporting high rf currents. The rf coils (30, 1) may be magnetically compensated and expansion controlled, and passive geometric compensation of magnetic susceptibility effects from a sample spinner stator may also be incorporated. Novel coil mounting techniques, including metallurgical bonds to ceramics and capturing by dielectric clam-shells, are also disclosed.

Abstract: Self-testing for a disease or physiological condition is achieved by having the individual being tested obtain a sample of physiological fluid, e.g., blood, urine, sputum or saliva, from him or herself. The sample is introduced into an assay system which produces a coded pattern indicative of the presence or a different coded pattern indicative of the absence of the disease or physiological condition. The individual then transmits the coded pattern to a remote location, for example by making a telephone call to an interpretation center, and receives from the remote location an interpretation of the coded pattern together with any counseling which may be appropriate in view of the interpretation of the coded pattern. The coded patterns are selected such that the individual may not interpret the test results without consulting the interpretation center.

Abstract: A process for effectively remediating soils contaminated with individual or mixture of metal ions is described. The process involves utilizing plants of the genus Pelargonium, particularly Pelargonium sp., to hyperaccumulate metal ions in their roots and shoots. These plants when grown on soils, which contain one or more of the metal ions, individually or in a complex mixture, will uptake the metal ions through their roots and translocate them to the shoots. This process thereby removes the metal ions from the soil. The harvested shoot and root biomass can be used for extraction of essential aromatic oils, and the residual oil-extracted biomass will be available for extraction and recycling of the metals. The process also describes the use of the above said plant(s) for remediating land-farming sites of petroleum industries, which are generally contaminated with a mixture of metal ions and organic contaminants.

Abstract: For conveying individually held products (3) in a network of conveying paths. (A, B), a holding element (4) is associated with each product (3) and is conveyed together with the product along the entire conveying route for the product (3) which route contains various conveying paths (A, B). Each holding element (4) comprises at least one first coupling part (1) for being coupled to a conveying element being movable along a given conveying path (A, B) and comprising a second coupling parts (2) or for being coupled to guides extending along the conveying paths. In transfer areas (U) in which products and holding means are transferred from one conveying path to another conveying path control means are provided for uncoupling holding elements (4) from conveying elements or guides of a first conveying path (A) and for coupling holding elements (4) to conveying elements or guides of a second conveying path (B).

Abstract: The claimed processing operation is used to process piece goods. Large numbers of at least similar objects are processed by feeding objects into the operation in streams (PS) of starting products (A), feeding the starting products and/or intermediate products in product streams (PS) to processing steps (7, 8, 12, 14, 15 . . . ) where they are processed and then carried away from the processing steps, and discharging the processed objects from the operation in streams of end products (EP). In the incoming and outgoing product streams individual products or product groups are conveyed in a sequence. At each processing step at least one property of a processed product or product group is changed. The claimed operation is characterized by sequence changes (4, 5, 6, 10, 13, 16, 17 . . . ) in which the sequence of products or product groups can be changed by transferring products in or out or combinations of both.