Patents Represented by Law Firm Oppenheimer Poms Smith Raymond Sun
  • Method for inhibiting chymopapain and papain enzyme activity with polysaccharides of animal origin
    Patent number: 5670358
    Abstract: The activities of chymopapain or papain in enzyme mixtures are inhibited by the addition of glycogen, hyaluronic acid, or desulfated heparin. The process for isolating viable hepatocytes or pancreatic cells by treatment with papain or chymopapain is improved by terminating the treatment by inhibiting the reaction with these polysaccharides. Similarly, the process for removing undesired tissue by treatment with papain or chymopapain is improved by terminating the treatment by inhibiting the reaction with these polysaccharides.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: September 23, 1997
    Assignee: Baxter International Inc.
    Inventors: Catherine T. Lee, Cynthia Zerfass, Tan Thanh Dinh, Minh T. Ma