Abstract: Disclosed are a spectrofluorimetrically detectable luminescent composition and processes for enhancing the luminescence of one or more lanthanide-containing macrocycles. The luminescent composition comprises a micelle-producing amount of at least one surfactant, at least one energy transfer acceptor lanthanide element macrocycle compound having an emission spectrum peak in the range from 500 to 950 nanometers, and a luminescence-enhancing amount of at least one energy transfer donor compound of yttrium or a 3-valent lanthanide element having atomic number 59-71, provided that the lanthanide element of said macrocycle compound and the lanthanide element of said energy transfer donor compound are not identical. The addition of gadolinium(III) in the presence of other solutes to both the prototype and the difunctionalized europium, samarium, and terbium macrocyclic complexes, which were taught in our U.S. Pat. Nos. 5,373,093 and 5,696,240, enhances their luminescence.

Abstract: There is disclosed a method of treating male impotence in a person in need of such treatment, which comprises enhancing the effectiveness of the person's immune system by the administration to such person of at least one aliphatic sulfur compound, preferably a sulfur-containing amino-acid derivative having the formula (I) in which A is hydrogen or a carboxymethylene -CH2CO2H group, B is hydrogen or an alkyl group having 1 to 3 carbon atoms, and X is hydrogen, or an acyl group —CO—R in which R is an alkyl group having 1 to 3 carbon atoms, or a pharmaceutically acceptable salt of such compound.

Abstract: Disclosed is a topical composition for relieving pain in a person in need of such relief, consisting essentially of an effective amount of a combination of at least one corticoid analgesic, at least one arylpropionic acid type analgesic, and at least one p-aminobenzoic acid ester type local anesthetic; an amount effective in enhancing the effectiveness in relieving pain of the combination of capsaicin, and an amount effective to increase the transmission thereof of through the skin of at least one phospholipid and at least one polyoxyethylenepolyoxypropylene copolymer.

Abstract: Disclosed is a one piece construction holder or container for irregularly shaped objects such as keys, dimensioned so as to fit within a card compartment of a conventional wallet, whereby said container is substantially rectangular and consists essentially of a rimmed top panel and a rimmed bottom panel integrally hinged together on one side, such that the hinge is thinner than either of the panels to which it is connected, and closure means on the opposite side from the hinge including a plug one one panel aligned with an accomodating hole on the other panel and mutually offset thumb access cutouts; the hinged top and bottom panels are disposed so as to hold the container open or snugly closed as required; the inside distance between the top panel and the bottom panel when the container is closed is defined by the width of the rim on each panel and is sufficient to accomodate from one to three keys placed in the container, and said distance taken together with the thickness of the top panel and the thickness

Abstract: Disclosed are compositions containing either aspartame or monosodium glutanate combined with an amino acid.

Abstract: Disclosed is the method of determining the effectiveness of an agent for the relief of elevation of the blood pressure, comprising the steps ofa) administering to a susceptible subject a quantity of a trigger substance reproducibly effective in producing within a period of six hours a perceptible increase in blood pressure lasting for at least twenty-four hours in the absence of treatment,b) administering to said subject having received said quantity of trigger substance a predetermined quantity of the agent whose effectiveness is to be determined,c) measuring the duration of said elevation of blood pressure upon administering said agent, andd) comparing the duration of said elevation with and without the administration of said agent.Also disclosed are effective quantities of certain nutrient substances which can reproducibly relieve elevated blood pressure produced in a susceptible subject by the administration of a trigger substance.

Abstract: Disclosed is the method of determining the effectiveness of an agent for relieving symptoms of the common cold, comprising the steps ofa) exposing a susceptible subject to vapors of a trigger substance reproducibly effective in producing within a period of 30 minutes a running nose lasting for at least 6 hours in the absence of treatment,b) administering to said subject having been exposed to a trigger substance a predetermined quantity of the agent whose effectiveness is to be determined,c) measuring the time required for the running nose to be abated, andd) comparing the time required for the running nose to be abated with and without the administration of said agent.Also disclosed are effective quantities of certain nutrient substances which can reproducibly relieve symptoms of the common cold produced in a susceptible subject by the administration of a trigger substance.

Abstract: Disclosed is the method of determining the effectiveness of an agent for the prevention of facial pimples or acne, comprising the steps ofa) administering to a susceptible subject a quantity of a trigger substance reproducibly effective in producing within a period of four hours the appearance of at least two pimples on the face of the subject lasting for at least eight hours in the absence of treatment,b) administering to said subject having received said quantity of trigger substance a predetermined quantity of the agent whose effectiveness is to be determined,c) measuring the number of pimples on the face of the subject upon administering said agent, andd) comparing the number of pimples with and without the administration of said agent.Also disclosed are effective quantities of certain nutrient substances which can reproducibly relieve pimples produced in a susceptible subject by the administration of a trigger substance.

Abstract: There is disclosed a pleasant tasting oral rinse composition and a method of using the same. The composition consists essentially of cayenne pepper, calendula, echinacea, goldenseal, propolis, vinegar, and water in certain proportions.

Abstract: Stabilizer compositions are provided to increase the resistance of a synthetic resin to deterioration upon heating, comprising in combination (A) a thiodipropionic acid ester of a dihydric alcohol having 2 to 20 carbon atoms and an alcohol or carboxylic acid chain terminator having 1 to 21 carbon atoms, and (B) a 700 to about 10,000 molecular weight ester of a polyhydric phenol with carbonic acid or with carbonic acid and another acid which can be an aliphatic dicarboxylic acid, phosphorous acid, phosphoric acid, boric acid, or an organophosphonic acid.Synthetic resins that can be stabilized with composition of the invention include polymers of alpha-olefins having 2 to 6 carbon atoms, vinyl chloride polymers, acrylonitrile-butadiene-styrene polymers, and terephthalic acid ester polymers.

Abstract: This invention relates to a new class of phenolic compounds containing a phosphorus acid ester group which are stabilizers for synthetic resins and to synthetic resin stabilizer compositions comprising these phenolic compounds as well as to synthetic resins stabilized with such phenolic compounds and with stabilizer compositions comprising these phenolic compounds along with known polymer stabilizers.

Abstract: New ortho-alkylhydroxybenzyl substituted propanediol compounds of carboxylic acids, aldehydes, ketones, phosphites, phosphates, and phosphonates are disclosed. The propanediol compounds have in the molecule from one to four preferably from one to three ortho-alkylhydroxybenzylpropanediol units, each of which carries one to two ortho-alkylhydroxybenzyl groups, and are highly effective stabilizers for a variety of synthetic resins.Stabilizer compositions comprising a orthoalkylhydroxybenzylpropanediol compound and a known polymer stabilizer, as well as synthetic resins stabilized with such stabilizer compositions, are also disclosed.

Abstract: An additive composition for improving the color stability of a vinyl chloride polymer stabilized with environmentally acceptable stabilizers comprises a 1,3-diketone or 1,3-diketone Na, K., Li, Mg, Zn, Ba, Ca, Sn, or Sr salt and an organic phosphite having the formula ##STR1## wherein R.sub.1 is a phenyl, cycloalkyl, t-butyl, or t-amyl group, R.sub.2 and R.sub.3 are each a hydrogen atom or phenyl, cycloalkyl, or an alkyl group having one to five carbon atoms, R.sub.4 is a hydrogen atom or a methyl group, and each of R.sub.5 and R.sub.6 independently is a hydrogen atom, an alkyl group having 1 to 18 carbon atoms, a cycloalkyl group having 5 to 20 carbon atoms, an aryl group having 6 to 12 carbon atoms, or an ether-substituted group having 3 to 80 carbon atoms and 1 to about 40 ether oxygen atoms.

Abstract: New polyhydric phenol coesters are disclosed of polyhydric phenols, having 2 to 3 phenolic hydroxyl groups and 1 to 3 benzenoid rings, with carbonic acid and an inorganic acid which can be phosphorous acid, phosphoric acid, and boric acid. The new coesters have molecular weights from 700 to about 10,000, preferably from 1200 to 7000, and are highly effective stabilizers for a variety of synthetic resins.Stabilizer compositions comprising a polyhydric phenol coester and a known polymer stabilizer, as well as synthetic resins stabilized with such stabilizer compositions, are also disclosed.

Abstract: The clarity of molded olefin polymer specimens is augmented by incorporating 0.005 to 5% by weight of the olefin polymer of a phenyl phosphate compound having the formula ##STR1## in which R.sub.1 and R.sub.2 are independently selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 18 carbon atoms, an alkoxy group having 1 to 18 carbon atoms, a cycloalkyl group having 5 to 12 carbon atoms, a phenyl group, a phenoxy group, and a group ##STR2## in which R.sub.5 is a hydrogen atom or an alkyl group having 1 to 18 carbon atoms; R.sub.3 is selected from the group consisting of an alkyl group having 1 to 18 carbon atoms, ##STR3## , and R.sub.4 ; and R.sub.4 is a hydrogen atom or a metal atom equivalent M.sub.1/a where a is the valence of the metal atom M.In the presence of such a phenyl phosphate, further improvements in clarity are obtained by also incorporating certain metal compounds.

Abstract: Stabilizer compositions comprising a polymer stabilizer and a carbonate ester of cyclic dihydroxy compounds protect synthetic resins against the harmful effects of light having a wavelength less than 400 nanometers. The carbonate ester can be represented by the formula ##STR1## in which a is a number from 1 to 50, A is hydrogen or ##STR2## B is R' or --G--OH, R and R' are independently alkyl, alkoxyalkyl, cycloalkyl, aryl, aryloxyalkyl, aralkyl, or alkaryl groups, and G in at least one occurrence is a residue of a cycloaliphatic or non-aromatic oxygen heterocyclic dihydroxy compound having 3 to 20 carbon atoms and 1 or 2 rings of 3 to 12 members, of which up to 4 can be oxygen. Additional occurrences of G can be aliphatic glycol or bisphenol residues if desired.

Abstract: There is disclosed a process for preparing 2,2,6,6-Tetramethyl-4-oxopiperidine (triacetoneamine), in which a hydrazine hydrohalide salt catalyzes the reaction of an acetone compound, for example acetone or diacetone alcohol, with an ammonia donor compound, for example ammonia or 2,2,4,4,6-pentamethyl-1,2,5,6-tetrahydropyrimidine (acetonine).

Abstract: An anti-yellowing additive is provided for environmentally acceptable stabilized vinyl chloride polymer compositions from which arsenic, beryllium, cadmium, lead, mercury, and thallium are substantially excluded, comprising at least one overbased sulfonate or phenolate compound of lithium, sodium, potassium, magnesium, calcium, strontium, barium, zinc, titanium, aluminum, zirconium, or tin, and a 1,3-diketone compound having 5 to 30 carbon atoms, which is a cyclic or open-chain 1,3-diketone or a lithium, sodium, potassium, magnesium, calcium, strontium, barium, zinc, aluminum, tin or zirconium salt thereof.

Abstract: 2,2,6,6-Tetramethyl-4-piperidone spiroketal carbinol compound of Formula I ##STR1## in which R.sub.1 represents hydrogen, alkyl of one to ten carbon atoms, or aralkyl of seven to ten carbon atoms, and R.sub.2 represents alkyl of one of one to six carbon atoms, is prepared by heating a mixture of a 2,2,6,6-tetramethyl-4-piperidone compound of Formula II ##STR2## or an acid addition salt thereof, and a 1,3 dioxane compound having the formula III ##STR3## in which R.sub.3 and R.sub.4 represent R.sub.1 or aryl of six to ten carbon atoms or taken together represent alkylene of four to eight carbon atoms, removing R.sub.3 R.sub.4 CO compound and recovering 2,2,6,6-tetramethyl-4-piperidonespiroketal compound.

Abstract: A 2,2,6,6-tetramethyl-4-piperidone spiroketal carbinol compound of Formula I ##STR1## in which R.sub.1 represents an alkyl group having from one to six carbon atoms, is prepared by heating a trimethylolalkane compound having the formula R.sub.1 --C(CH.sub.2 OH).sub.3 with a 2,2,6,6-tetramethyl-4-piperidone ketal compound of Formula II ##STR2## in which R.sub.2 represents an alkyl group having from one to twelve carbon atoms or an ether-interrupted alkyl group having from three to twelve carbon atoms and from one to two ether oxygen atoms, removing alcohol R.sub.2 OH, and recovering 2,2,6,6-tetramethyl-4-piperidone spiroketal carbinol compound of Formula I.