Patents Represented by Attorney Pamela Ancona

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  • Benzamide inhibitors of the P2Xreceptor
    Patent number: 7071223
    Abstract: The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1–R3 are as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: July 4, 2006
    Assignee: Pfizer, Inc.
    Inventors: Mark A Dombroski, Allen J. Duplantier, Chakrapani Subramanyam