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  • Flavivirus NS5A proteins for the treatment of HIV
    Patent number: 8268778
    Abstract: GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving a -GBV-C NS5A peptide or polypeptide for inhibiting and treating HIV infections.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: September 18, 2012
    Assignee: University of Iowa Research Foundation
    Inventors: James McLinden, Jinhua Xiang, Jack T. Stapleton