Abstract: An isolated protein sequence or peptide from the E2, E6 or E7 early coding region of human papillomavirus (HPV) that is soluble in an aqueous medium, and characterized by a relative paucity of tryptophan, methionine and cysteine residues, and a relative abundance of glycine and asparagine residues. Also disclosed are isolated protein sequences or peptides from the E2, E6 or E7 early coding regions of HPV 16 and 18 and methodologies for detecting or diagnosing cancer or cellular abnormalities. Detection or diagnosis of Cancer or cellular abnormalities may include detecting or diagnosing pre-cancerous or pre-malignant conditions, cervical dysplasia, cervical carcinoma, koilocytosis, hyperkeratosis, intraepithelial lesions, and other cancers.

Abstract: An apparatus and methods for chlorine dioxide generation. The chlorine dioxide apparatus may comprise a plurality of metering pumps for delivering a plurality of reactant chemicals. The reactant chemicals are preferably delivered to a reaction column through inlet ports where the reactants are mixed to form the desired reactants. A synchronizer may control the metering pump action to provide synchronized delivery of the plurality of reactant chemicals to the reaction column.