Abstract: The present invention provides novel methods of making a non-corrosive base solution for use as an alkalinity increasing agent and/or antioxidant. The present invention further provides novel compositions and methods which can be used to provide relief from disorders related to or complicated by acidosis or excessive free radical or other reactive oxygen species production including, but not limited to, gout, Lesch-Nyhan syndrome, hemochromatosis, Alzheimer's, amyotropic lateral sclerosis, arthritis, atherosclerosis, cancer, cataracts, chronic obstructive pulmonary disease, diabetes, cellulitis, coronary artery disease, heart failure, hypertension, inflammatory bowel disease, macular degeneration, multiple sclerosis, Parkinson's, Reynaud's phenomenon, reperfusion injury, pancreatic impairment, skin infections, Hepatitis C, methicillin-resistant Staphylococcus aureus and infection.
Abstract: The invention provides novel arylbicyclo[3.1.0]hexylamines, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including but not limited to depression and anxiety.
Abstract: The present invention provides identification of inhibitors of inhibitors of differentiation (Id) for use in the treatment and prevention of diseases in mammals. The inhibitors of Id are effective alone in the treatment of a variety of cellular proliferative disorders including, but not limited to, diseases such as cancer, arthritis, age-related macular degeneration, psoriasis, neoplasms, angiomas, endometriosis, obesity, age-related macular degeneration, retinopathies, restenosis, scaring, fibrogenesis, fibrosis, cardiac remodeling, pulmonary fibrosis, scleroderma, failure associated with myocardial infarction, keloids, fibroid tumors and stenting.
Abstract: A synthesis of an energetic prepolymer used as a high-energy binder for an insensitive and high performance explosive is disclosed. More specifically, provided are a novel compound 2-nitratoethyl oxirane expressed by formula III, a novel compound poly(2-nitratoethyl oxirane) expressed by formula IV, obtained by polymerization of 2-nitratoethyl oxirane used as a monomer and a preparation method thereof. The compound, used as an energetic prepolymer and a monomer for preparation thereof can substitute for existing poly(glycidyl nitrate) (PGN) which has been known to be a promising one having the best performance among existing energetic prepolymers, but which has a problem to be self-decomposed after synthesis of polyurethane elastomer, to solve this problem.
Type:
Grant
Filed:
April 28, 2009
Date of Patent:
February 1, 2011
Assignee:
Agency for Defense Development A Non Profit Korean Organization
Inventors:
Jin Seuk Kim, Jin Rai Cho, Keun Deuk Lee, Jeong-Kook Kim
Abstract: Disclosed are an integrated authoring system for an electronic technical manual and a paper technical manual using logistics support analysis data, which is capable of authoring an interactive electronic technical manual (IETM) of Class IV level and a paper technical manual at the same time. The integrated authoring system for an electronic technical manual and a paper technical manual using logistics support analysis data comprises: an iCAST-LSA (intelligent computer based acquisition support tool-logistics support analysis) module; a TMM (Technical Manual Management) module for performing a technical manual management function by importing from the DB of the iCAST-LSA module or exporting to the DB of the iCAST-LSA module; an illustrated drawing manager module; and a TMA (Technical Manual Author) module for performing a manual author manager function for sending and receiving illustrated drawings (ID) or CGM data to and from the illustrated drawing manager module.
Type:
Grant
Filed:
August 17, 2005
Date of Patent:
July 13, 2010
Assignee:
Agency for Defense Development
Inventors:
Myung-Jin Jang, Byung-Jik Yoo, Kwang-Taek Lee, Hyun-Jun Ju