Patents Represented by Attorney, Agent or Law Firm Patricia A. McDaniels
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Patent number: 7442853Abstract: A transgenic plant transformed by a Protein Kinase Stress-Related Protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in the plant's increased growth under normal or stress conditions and/or increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRPs, and isolated nucleic acid coding PKSRPs, and vectors and host cells containing the latter.Type: GrantFiled: April 13, 2006Date of Patent: October 28, 2008Assignee: BASF Plant Science GmbHInventors: Damian Allen, Ruoying Chen, Amber Shirley
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Patent number: 7439417Abstract: A transgenic plant transformed by a transcription factor stress-related protein (TFSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated TFSRP, and isolated nucleic acid coding TFSRP, and vectors and host cells containing the latter. Further provided are methods of producing transgenic plants expressing TFSRP, methods of increasing expression of other genes of interest using the TFSRP, methods of identifying novel TFSRP, and methods of modifying the expression of TFSRP in plants.Type: GrantFiled: May 24, 2007Date of Patent: October 21, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Nocha Van Thielen, Ruoying Chen
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Patent number: 7435875Abstract: A transgenic plant transformed by a GTP Binding Stress-Related Protein (GBSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated GBSRPs, and isolated nucleic acid coding GBSRPs, and vectors and host cells containing the latter.Type: GrantFiled: December 19, 2007Date of Patent: October 14, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Hans J. Bohnert, Nocha van Thielen, Ruoying Chen
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Patent number: 7427698Abstract: A transgenic plant transformed by a Protein Kinase Stress-Related Polypeptide (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRPs, and isolated nucleic acid coding PKSRPs, and vectors and host cells containing the latter.Type: GrantFiled: October 26, 2007Date of Patent: September 23, 2008Assignee: BASF Plant Science GmbHInventors: Nocha Van Thielen, Oswaldo de Costa e Silva, Ruoying Chen
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Patent number: 7427696Abstract: A transgenic plant transformed by a Transcription Factor Stress-Related Protein (TFSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated TFSRPs, and isolated nucleic acid coding TFSRPs, and vectors and host cells containing the latter.Type: GrantFiled: December 4, 2006Date of Patent: September 23, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Hans J. Bohnert, Nocha van Thielen, Ruoying Chen
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Patent number: 7425665Abstract: A transgenic plant transformed by a protein kinase stress-related protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRP, and isolated nucleic acid coding PKSRP, and vectors and host cells containing the latter. Further provided are methods of producing transgenic plants expressing PKSRP, and methods of identifying novel PKSRP and methods of modifying the expression of PKSRP in plants.Type: GrantFiled: January 10, 2007Date of Patent: September 16, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Manabu Ishitani, Stefan Henkes, Nocha van Thielen, Ruoying Chen
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Patent number: 7425666Abstract: A transgenic plant transformed by a Transcription Factor Stress-Related Protein (TFSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated TFSRPs, and isolated nucleic acid coding TFSRPs, and vectors and host cells containing the latter.Type: GrantFiled: May 23, 2007Date of Patent: September 16, 2008Assignee: BASF Plant Science GmbHInventors: Oswaldo da Costa e Silva, Hans J. Bohnert, Nocha Van Thielen, Ruoying Chen
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Patent number: 7423196Abstract: A transgenic plant transformed with an 'SLSRP coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased growth under water-limited conditions and/or increased tolerance to an environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated SLSRPs, and isolated SLSRP coding nucleic acids, and vectors and host cells containing the latter.Type: GrantFiled: October 19, 2005Date of Patent: September 9, 2008Assignee: BASF Plant Science GmbHInventors: Damian Allen, Lori V. Mills, Nocha van Thielen, Oswaldo da Costa e Silva
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Patent number: 7399903Abstract: A transgenic plant transformed by a Vesicle Trafficking Stress-Related Polypeptide (VTSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in the plant's increased growth and/or increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated VTSRPs, and isolated nucleic acid coding VTSRPs and vectors and host cells containing the latter.Type: GrantFiled: October 27, 2005Date of Patent: July 15, 2008Assignee: BASF Plant Science GmbHInventors: Xi-Qing Wang, Damian Allen, Chen Ruoying, Lori V. Mills, Nocha van Thielen, Oswaldo da Costa e Silva, Bryan McKersie
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Patent number: 7399904Abstract: A transgenic plant transformed by a casein kinase Stress-Related Polypeptide (CKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated CKSRPs, and isolated nucleic acid coding CKSRPs, and vectors and host cells containing the latter.Type: GrantFiled: April 20, 2007Date of Patent: July 15, 2008Assignee: BASF Plant Science GmbHInventor: Amber Shirley
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Patent number: 7303919Abstract: A transgenic plant transformed by a Protein Kinase Stress-Related Polypeptide (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PKSRPs, and isolated nucleic acid coding PKSRPs, and vectors and host cells containing the latter.Type: GrantFiled: December 12, 2006Date of Patent: December 4, 2007Assignee: BASF Plant Science GmbHInventors: Nocha Van Thielen, Oswaldo da Costa e Silva, Ruoying Chen
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Patent number: 7285703Abstract: The invention relates to hosts containing constructs with genes from the starch pathway. More typically the present invention relates to bacterial hosts that form plant like starches. Additionally the present invention relates to plant hosts that have genes from the starch pathway. The invention further relates to the starches produced by said hosts.Type: GrantFiled: January 11, 2006Date of Patent: October 23, 2007Assignee: BASF Plant Science GmbHInventors: Hanping Guan, Peter Keeling, Angela McKean
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Patent number: 7169982Abstract: This invention relates to a method of producing a starch with unique functionality in plants through mutableness, and/or using biotechnology, and/or breeding practices. Further the invention relates to the starch from maize plants and/or other plants which produce starch storing organs which contain low amylose starch which has an amylose content between 1.5% and 15% and preferably between 1.5% and 10% and most preferably 1.5 and 8%. The invention includes starch extracted from such grain due to at least one mutation induced by ethyl methanesulfonate. Additionally, the invention uses a biotechnology approach involving controlling the activity of the granule bound starch synthase enzyme in starch storing organ. The invention includes the use of the starch for its cooking, paste, and gel properties.Type: GrantFiled: October 17, 2002Date of Patent: January 30, 2007Assignee: Basf Plant Science GmbHInventors: Jeffrey D. Klucinec, Peter L. Keeling, Padma Commuri, Ming-Tang Chang
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Patent number: 7141659Abstract: The present invention relates to a recombinant nucleic acid encoding a hybrid polypeptide which comprises a transit peptide for the translocation of the polypeptide into an appropriate organelles such as plastids, a starch-encapsulating region from maize starch synthase and a payload polypeptide, wherein said payload polypeptide can be either N- or C-terminal to the starch encapsulating region. The invention also relates to the expression vectors comprising said nucleic acid, and hosts comprising the said vector. Also, the invention encompasses methods of producing the hybrid polypeptide thereof from starch and particularly from starch granules, and industrial uses of the payload polypeptide recombinantly produced in said hybrid polypeptide wherein said payload polypeptide is a biologically active molecule.Type: GrantFiled: July 28, 2003Date of Patent: November 28, 2006Assignee: BASF Plant Science GmbHInventors: Peter Keeling, Hanping Guan
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Patent number: 7087261Abstract: The present invention provides grain, seed, feed made from the grain or seed, pet food made from the grain, and food products made from the grain. The grain may be maize grain with the following characteristics: oil burdened, elevated protein content, and low phytate levels. The combination of oil burdened, protein laden, decreased phytate characteristics in grain makes a grain that provides more calories, protein and phosphorus and other nutrients to the feeding animal. Pet foods, and animal feeds and corn food products made of the present invention will provide increased nutrition because of the increased bioavailability of the components of the grain.Type: GrantFiled: July 2, 2004Date of Patent: August 8, 2006Assignee: BASF Plant Science L.L.C.Inventors: Ming-Tang Chang, Peter L. Keeling, Edward P. Wilheim, Jerry C. Weigel
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Patent number: 6774288Abstract: The present invention provides grain, seed, feed made from the grain or seed, petfood made from the grain, and food products made from the grain. The grain may be maize grain with the following characteristics: oil burdened, elevated protein content, and low phytate levels. The combination of oil burdened, protein laden, decreased phytate characteristics in grain makes a grain that provides more calories, protein and phosphorus and other nutrients to the feeding animal. Pet foods, and animal feds and corn food products made of the present invention will provide increased nutrition because of the increased bioavailability of the components of the grain.Type: GrantFiled: January 6, 2000Date of Patent: August 10, 2004Assignee: BASF Plant Science L.L.C.Inventors: Ming-Tang Chang, Peter L. Keeling, Edward P. Wilhelm, Jerry C. Weigel
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Patent number: 6358491Abstract: The invention provides novel peptide-based pharmacophores and compounds which bind somatostatin receptors with high affinity and which exhibit improved pharmacokinetic properties over known somatostatin analogs. The pharmacophores and compounds of the invention may be used in labeled or unlabeled form for diagnosing and/or treating somatostatin responsive diseases. The invention also provides radiopharmaceuticals and kits comprising these compounds, as well as methods for diagnosing and/or treating somatostatin receptor mediated diseases.Type: GrantFiled: September 16, 1999Date of Patent: March 19, 2002Assignee: Berlex Laboratories, Inc.Inventors: John Lister-James, Richard T. Dean, Daniel A. Pearson, David M. Wilson
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Patent number: 6248304Abstract: This invention provides scintigraphic imaging agents and reagents for preparing said agents, methods for radiolabeling said reagents and kits containing non-radioactive reagents and other components for the convenient preparation of the scintigraphic imaging agents. More specifically, the invention provides scintigraphic imaging agents that are radiolabeled compounds which bind with high affinity to GPIIb/IIIa receptors on activated platelets and using such radiolabeled compounds derivatives to image sites in a mammalian body.Type: GrantFiled: September 27, 1996Date of Patent: June 19, 2001Assignee: Berlex Laboratories, Inc.Inventors: John Lister-James, Richard T. Dean
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Patent number: 6241965Abstract: This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labelled radiodiagnostic agents. Specifically, the invention relates to linear peptide derivatives and analogs of somatostatin, and embodiments of such peptides radiolabelled with a radioisotope, as well as methods and kits for making, radiolabelling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to linear peptide derivatives and analogues of somatostatin radiolabelled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention also specicically relates to linear peptide derivatives and analogues of somatostatin radiolabelled with cytotoxic radioisotopes such as rhenium-186 (186Re) and rhenium-188 (188Re) for use as radiotherapeutic agents. Methods and kits for making, radiolabelling and using such peptides diagnostically and therapeutically in a mammalian body are also provided.Type: GrantFiled: April 22, 1996Date of Patent: June 5, 2001Assignee: Diatide, Inc.Inventors: Richard T. Dean, William McBride
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Patent number: 6214316Abstract: This invention relates to therapeutic reagents and peptides, including radiotherapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic agents. Specifically, the invention relates to cyclic peptide derivatives and analogs of somatostatin, and embodiments of such peptides radiolabeled with a radioisotope, as well as methods and kits for making, radiolabeling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention also specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with cytotoxic radioisotopes such as rhenium-186 (186Re) and rhenium-188 (188Re) for use as radiotherapeutic agents.Type: GrantFiled: October 19, 1999Date of Patent: April 10, 2001Assignee: Diatide, Inc.Inventor: Richard T. Dean