Patents Represented by Attorney, Agent or Law Firm Patricia McDaniels
  • Somatostatin analogs
    Patent number: 6358491
    Abstract: The invention provides novel peptide-based pharmacophores and compounds which bind somatostatin receptors with high affinity and which exhibit improved pharmacokinetic properties over known somatostatin analogs. The pharmacophores and compounds of the invention may be used in labeled or unlabeled form for diagnosing and/or treating somatostatin responsive diseases. The invention also provides radiopharmaceuticals and kits comprising these compounds, as well as methods for diagnosing and/or treating somatostatin receptor mediated diseases.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: March 19, 2002
    Assignee: Berlex Laboratories, Inc.
    Inventors: John Lister-James, Richard T. Dean, Daniel A. Pearson, David M. Wilson
  • Scintigraphic imaging agents
    Patent number: 6248304
    Abstract: This invention provides scintigraphic imaging agents and reagents for preparing said agents, methods for radiolabeling said reagents and kits containing non-radioactive reagents and other components for the convenient preparation of the scintigraphic imaging agents. More specifically, the invention provides scintigraphic imaging agents that are radiolabeled compounds which bind with high affinity to GPIIb/IIIa receptors on activated platelets and using such radiolabeled compounds derivatives to image sites in a mammalian body.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: June 19, 2001
    Assignee: Berlex Laboratories, Inc.
    Inventors: John Lister-James, Richard T. Dean