Abstract: A sterilizable, plastic medical container has a body section formed of thin, multi layer film. The film has a first layer formed of cross-linkable plastic free or essentially free of extractable plasticizers, such as poly(ethylene vinyl acetate), and a second layer formed of a substantially non-cross-linkable plastic having a higher melting temperature than the first layer, such as high density polyethylene. The first layer is inwardly oriented in contact with the contents of the container. A port formed of the same plastic can be heat sealed to the body section. The container is irradiated to effect cross-linking, filled with fluid, and the port sealed. The fluid filled container can then be heat or steam sterilized.