Patents Represented by Attorney Paul Flattery
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Patent number: 5551850Abstract: A medical infusion pump (10) using a pump chamber cassette (86) has a housing (20,22) defining a pump chamber cassette receptacle (84) and a pump driving mechanism (250) for propelling liquid through the pump chamber cassette. A door (50) holds the pump chamber cassette (86) within the cassette receptacle (84) in an operative position relative to the driving mechanism (250). The cassette includes an elastomeric conduit (132), a frame (134) and clips (146,148) for attaching the elastomeric conduit (132) to the frame (134) for holding the elastomeric conduit (132) in a select position relative to the pump driving mechanism (250) of the infusion pump upon placement of the cassette (86) in an operative position relative to the pump driving mechanism (250).Type: GrantFiled: May 11, 1995Date of Patent: September 3, 1996Assignee: Baxter International Inc.Inventors: Mark E. Williamson, Jerry W. Newbrough, Robert L. Anderson, Jeffrey P. Castleberry, Warren P. Heim, Steve W. Stracener
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Patent number: 5503139Abstract: A nebulizer (10) has a nebulizer top (12) defining an aerosol outlet (66) and a reservoir bottom (14) defining a liquid reservoir (21) and a threaded connection (38,68) between the reservoir bottom (14) and the nebulizer top (12). A nebulizing structure (24,46) within the nebulizer provides an aerosol to the aerosol outlet (66). A continuous flow adaptor (16) for the nebulizer has a side wall (90) with first and second open ends (94,100) defining a spacer interior. An orifice (116) in the side wall (90) of the adaptor (16) allows for fluid communication with the adaptor (16) interior from outside of the adaptor (16). A luer connector (118) is provided on the side wall (90) of the adaptor (16) for connecting the orifice (116) in fluid tight communication with a fluid supply. The adaptor (16) includes threads (92,98) proximate the first and second open ends (24,100) for cooperatively engaging the threaded portions (38,68) of the reservoir top (12) and reservoir bottom (14).Type: GrantFiled: February 2, 1994Date of Patent: April 2, 1996Inventors: Michael D. McMahon, Andre M. Rustad
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Patent number: 4850978Abstract: A cartridge 444, 644, 744 is adapted for mounting upon a receptacle 442, 642 in a parenterial fluid administration set 420 for delivering a drug or other beneficial agent to a patient. The cartridge 444, 644, 744 includes a beneficial agent-containing chamber 606 slidable from a first, pre-use position to a second, post-use position. The cartridge includes a hollow tube 496 in which the chamber 606 is at least partially mounted. At least one cannula 500 is mounted to the hollow tube and extends opposite the chamber. A protective cover or cap 530 maintains a chamber protective position that prevents inadvertent movement of the chamber that would accidentally engage the cartridge chamber with a flow path member, such as the cannula. The cover is removed in order to engage the chamber.Type: GrantFiled: October 29, 1987Date of Patent: July 25, 1989Assignee: Baxter International Inc.Inventors: Thomas E. Dudar, Brian D. Zdeb
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Patent number: 4840017Abstract: A flexible collapsible container is filled with fluid by connecting a fluid conduit to a tubular port which communicates through one of the walls of the container to the container interior, and rupturing a sealing diaphragm that closes the bore of the tubular port. One then passes fluid through the conduit to fill the container. Thereafter, one seals either or both the tubular port and plastic wall which carries it to the other, opposed plastic wall of the container with seal line means to close off flow communication between the bore of the tubular port and a major portion of the container interior which contains the fluid. The effect of this is to block flow communication between the bore and the fluid so that the contents of the container remain sealed on disengagement of the fluid conduit from the tubular port.Type: GrantFiled: August 3, 1987Date of Patent: June 20, 1989Assignee: Baxter Healthcare CorporationInventors: Robert A. Miller, Albert L. Stone
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Patent number: 4823833Abstract: The present invention provides a sterile, unitized, economical device furnishing a fluid path between a plurality of solutions to be compounded and a receiving container. The device includes a plurality of fluid connectors and fluid lines sealingly connected to respective pump fittings which provide individual paths to a common junction block.The common junction block includes a portion for receiving fluid lines and preventing them from crimping thereby maintaining fluid flow. The block also includes an exit port for providing a sealingly sterile connection to the receiving container. Further, a closure is provided to protect the exit port from contamination when the port is not providing fluid communication to the receiving container.Type: GrantFiled: September 11, 1984Date of Patent: April 25, 1989Assignee: Baxter Healthcare CorporationInventors: Lawrence R. Hogan, Herbert Mittleman, Edward G. Oilschlager, Ellen Rouch, William L. Rudzena
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Patent number: 4789014Abstract: A device is described for accurately transferring multiple individual fluids from multiple source containers into a single receiving container. Fluid flows from the multiple source containers through individual fluid conduits to a chamber having a single fluid outlet conduit. The fluid outlet conduit is in fluid communication with a single receiving container. A pressure conduit is in communication with the chamber for alternately creating positive and negative pressures in the chamber to cause fluid to flow from the individual source containers into the chamber, and to cause fluid flow from the chamber into the receiving container in response to commands from a controller.Type: GrantFiled: January 12, 1988Date of Patent: December 6, 1988Assignee: Baxter International Inc.Inventors: Aleandro DiGianfilippo, James R. Hitchcock, Robert E. Lewis, Randall A. Zielsdorf, James P. Vos, Rudolph Starai, Michael J. Becker, Donald W. Warner, Leon Huang
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Patent number: 4739039Abstract: An improved method of recovering antihemophilic factor (AHF) from cryoprecipitated blood plasma is provided. The improved method incorporates the addition of a calcium ion source during the step of cold precipitation of fibrinogen and fibronectin contaminants, as well as the addition of polyethylene glycol (PEG) at one of various stages of the recovery process. PEG may be added during the cold precipitation of fibrinogen and fibronectin, during the precipitation of AHF, or prior to the filtration of AHF solution. The method of the present invention results in a final AHF product having greatly increased solubility, higher specific activity, and lower fibrinogen and fibronectin content.Type: GrantFiled: July 15, 1987Date of Patent: April 19, 1988Assignee: Baxter Travenol Laboratories, Inc.Inventors: Rodolfo A. Vasquez, Maria E. Co-Sarno, Clifford R. Graf
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Patent number: 4722850Abstract: A disposable container is provided that has a semi-rigid generally concave body and a collapsible panel sealing an open mouth of the semi-rigid body. An access assembly is mounted to the outside surface of the semi-rigid body. Liquid sealed within the semi-rigid body by the collapsible panel is removed through the access assembly, during which removal the collapsible panel collapses to generally conform to the generally concaved shape of the body. Space efficient assemblies of these disposable containers are also provided.Type: GrantFiled: April 24, 1986Date of Patent: February 2, 1988Assignee: Baxter Travenol Laboratories, Inc.Inventors: Leonard A. White, James L. Cabernoch
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Patent number: 4718467Abstract: A novel technique of connecting two or more pumping modules under a laminar flow hood is described. The technique includes the use of a novel manifold which is specifically designed to enhance laminar air flow across the outlet port of the manifold when connected to one of the pumping modules. The manifold includes a cylindrical housing having an axially extending outlet port, and two or more sets of radially extending inlet ports eminate from the cylindrical housing. The inlet ports of each set are closely spaced with respect to one another to minimize the length of the cylindrical housing. A common fluid channel extends substantially through the length of the cylindrical housing to connect each of the inlet ports to the single outlet port.Type: GrantFiled: May 30, 1986Date of Patent: January 12, 1988Assignee: Baxter Travenol Laboratories, Inc.Inventors: Aleandro Di Gianfilippo, Michael Becker, James R. Hitchcock, Jr.
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Patent number: 4712590Abstract: A device for connecting two or more bulk compounding systems for mixing hyperalimentation solutions is described. The device allows electrical signals from each bulk compounding system to be connected to one another so that each bulk compounding system may act in concert with other bulk compounding systems to fill an individual receiving container with minimal modifications to the internal circuitry of an individual bulk compounding system.Type: GrantFiled: May 30, 1986Date of Patent: December 15, 1987Assignee: Baxter Travenol Laboratories, Inc.Inventor: Aleandro Di Gianfilippo
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Patent number: 4690758Abstract: A mass transfer device (60) includes a hollow fiber bundle (10) comprising a generally cylindrical core (14) having opposed ends, a plurality of layers of hollow fiber (12) that have been wound around the core, and binding means (48a, 48b, 48c) such as double- sided pressure-sensitive tape that have been wound around the layers of hollow fiber in a plurality of longitudinally spaced locations along the core and intermediate the opposite ends of the core for providing longitudinally spaced support means for the hollow fiber bundle. The hollow fiber bundle is enclosed in a housing (62) having an inner wall (80) which defines a generally circular opening for receiving the hollow fiber bundle except that the inner wall adjacent a fluid outlet manifold (74) includes an expansion volume (82) for the hollow fibers that are adjacent that fluid outlet manifold.Type: GrantFiled: November 5, 1984Date of Patent: September 1, 1987Assignee: Baxter Travenol Laboratories, Inc.Inventors: Ronald J. Leonard, Kenneth M. Johnson
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Patent number: 4688753Abstract: A flexible tubing occluding device is provided for releasably occluding flexible tubing. The tubing occluding device includes housing that is adapted to receive the tubing and defines a tubing occluding surface against which a transverse section of the tubing is transversely urged and compressed when in an occluded position. A wedge-shaped tongue member is provided for urging the transverse section of the tubing against the tubing occluding surface. The geometry of the tubing occluding surface and the wedge-shaped tongue member cooperate to distribute a relatively low amount of force at the center portion of the occluded tubing and a relatively large force at the distal ends of the occluded tubing, utilizing the mechanical advantage of the wedge-shaped tongue member.Type: GrantFiled: April 2, 1986Date of Patent: August 25, 1987Assignee: Baxter Travenol Laboratories, Inc.Inventors: Charles C. Tseng, Kenneth Lynn
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Patent number: 4485064Abstract: Containers used for storing and dispensing liquids for medical applications include a closure, and medical connection device include cooperating connector members. An article of manufacture and a method are provided where a plastic outer closure is applied over container closures or over connection devices. The application of the plastic outer closure exerts an antibacterial effect in the juncture area defined by the interface of the outer closure and the container inner closure and neck, or defined by the interface of the outer closure and the connection site of the connector members. The outer closure is of a type of plastic that releases an antibacterial agent, which exerts an antibacterial effect in the juncture area.Type: GrantFiled: April 6, 1982Date of Patent: November 27, 1984Assignee: Baxter Travenol Laboratories, Inc.Inventor: Dean Laurin
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Patent number: 4467930Abstract: Containers used for storing and dispensing liquids for medical applications and formed in a one-piece, molded construction include a neck defining a dispensing outlet and an annular lip, a closure for the outlet and a frangible section coupling the closure to the neck. An article of manufacture and a method are provided where a frangible section couples the closure to the neck and defines an annular channel between the outlet lip and the closure. Completing the article of manufacture and method, the neck has an overmold which engages the closure whereby the molding of the overmold may tend to reduce the bio-burden at the area of contact of the overmold and the neck and whereby displacement of the overmold ruptures the frangible section permitting removal of the overmold and closure for opening of the container.Type: GrantFiled: April 6, 1982Date of Patent: August 28, 1984Assignee: Baxter Travenol Laboratories, Inc.Inventors: William J. Schnell, Thomas A. Fowles, Albert Henhapl
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Patent number: 4451259Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable ester such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.Type: GrantFiled: December 19, 1979Date of Patent: May 29, 1984Assignee: Baxter Travenol Laboratories, Inc.Inventors: Ulrich C. Geissler, Gerald A. Grode, William J. Stith, Ronald A. Williams
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Patent number: 4415393Abstract: A method of manufacturing a tear-off port protector for a container comprises placing flexible, typically extruded tubing on a mandrel that fills the bore of the tubing, with the tubing preferably outwardly stretched by the mandrel. A cutting blade is spaced a predetermined distance of less than the tubing wall thickness from the mandrel. One then causes the cutting blade to form an annular cut about the tubing, while maintaining the predetermined distance, and thereafter one removes the tubing from the mandrel.Type: GrantFiled: October 22, 1981Date of Patent: November 15, 1983Assignee: Baxter Travenol Laboratories, Inc.Inventor: Robert G. Grimes
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Patent number: 4382083Abstract: Patients having a clotting factor defect can be successfully treated by the administration of a composition containing effective hemostatic amounts of factor VIIa. Preferably, the factor VIIa is substantially free of factors IXa and Xa. Procedures for preparing the above therapeutic compositions are also described.Type: GrantFiled: June 25, 1981Date of Patent: May 3, 1983Assignee: Baxter Travenol Laboratories, Inc.Inventor: William R. Thomas
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Patent number: 4318813Abstract: A membrane plasmapheresis module (10) comprises semipermeable membrane means (11) capable of permitting blood plasma to pass therethrough while preventing the passage of blood cells, and sealed housing means (18, 19) defining a blood inlet port (43) and blood outlet port (44) positioned adjacent opposite ends of a first flow path (60) extending along one side of the membrane (11). The housing (18, 19) also defines a plasma outlet port (38) adjacent one end of separate, second flow paths (62) extending along the other side of the membrane (11). The membrane (11) may be folded together about a fold line (12) to define a pair of membrane portions (14, 16) lying against each other. The first flow path (60) extends between the membrane portions (14, 16) and the second flow path (62) may optionally extend between each membrane portion (14, 16) and a wall of the sealed housing means (18, 19), or alternatively an adjacent fold (12) of the membrane portion.Type: GrantFiled: June 30, 1980Date of Patent: March 9, 1982Assignee: Baxter Travenol Laboratories, Inc.Inventors: William Edelman, James R. Hitchcock, Jr., William J. Schnell
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Patent number: D311954Type: GrantFiled: February 19, 1987Date of Patent: November 6, 1990Inventor: Dean Kamen
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Patent number: D314434Type: GrantFiled: February 19, 1987Date of Patent: February 5, 1991Inventor: Dean Kamen