Patents Represented by Attorney, Agent or Law Firm Paul G. Ginsburg
  • Synthesis of carbamate ketolide antibiotics
    Patent number: 6403776
    Abstract: The invention relates to a method of preparing a macrolide antibiotic of the formula wherein R1, R2, R3, R4, R5 are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: June 11, 2002
    Assignee: Pfizer Inc.
    Inventors: David H. B. Ripin, Brian C. Vanderplas, Takushi Kaneko, William T. McMillen, Robert W. McLaughlin
  • Isochroman compounds and their production process
    Patent number: 6177458
    Abstract: This invention relates to the isochroman compound of formula (I) and its pharmaceutically acceptable salts, which are useful as an amyloid aggregation inhibitor and for treating Alzheimer's disease. This invention also relates to processes for producing the isochroman compound, which comprises cultivating Penicillium simplicissimum FERM BP-6357 and then isolating the isochroman compound from the fermentation broth. The present invention also relates to a pharmaceutical composition comprising the isochroman compound.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: January 23, 2001
    Assignee: Pfizer Inc
    Inventors: Hideo Hirai, Toshio Ichiba, Hiroko Tonai
  • Multicomponent clostridial vaccines using saponin adjuvants
    Patent number: 6083512
    Abstract: Novel multicomponent clostridial vaccine formulations using readily dispersible, non-depot adjuvants, such as saponin, are disclosed. The vaccines can be administered to cattle intramusculary or subcutaneously without the severe persistent local reactions, such as granulomas, abscesses, and scarring, normally seen with other multicomponent clostridial vaccines.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: July 4, 2000
    Inventor: David S. Roberts
  • Pharmaceutical tablet
    Patent number: D433122
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: October 31, 2000
    Assignee: Pfizer Inc.
    Inventor: Robert Burrows
  • Pharmaceutical tablet
    Patent number: D433499
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: November 7, 2000
    Assignee: Pfizer Inc
    Inventor: Robert Burrows
  • Pharmaceutical tablet
    Patent number: D433501
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: November 7, 2000
    Assignee: Pfizer Inc
    Inventor: Robert Burrows
  • Pharmaceutical tablet
    Patent number: D434135
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: November 21, 2000
    Assignee: Pfizer Inc
    Inventor: Robert Burrows