Abstract: A multivalent antigen binding protein comprises a single polypeptide chain comprising, in series, two or more single domain binding units which are preferably heavy chain variable domains derived from an immunoglobulin naturally devoid of light chains. Methods for their production and uses thereof, in particular for diagnosis, immunoassay and purification methods are disclosed.
Type:
Grant
Filed:
April 27, 2000
Date of Patent:
December 30, 2003
Assignee:
Unilever Patent Holdings B.V.
Inventors:
Leon Gerardus Frenken, Steven Howell, Adrianus Marinus Ledeboer, Cornelis P van der Logt
Abstract: An asphalt-based composition comprising an air-blown blend of hard asphalt flux and the residue obtained by vacuum distilling the product obtained by the hydrogenation of asphalt flux, the composition meeting coating grade asphalt specifications.
Abstract: A coating composition substantially prevents fraying of glass fiber yarn packages. The composition is composed of an aqueous solution of a resin formed of the hydrolysis product of a copolymer of vinyl aromatic monomer and maleic anhydride, an organo silane glass fiber anchoring agent and an effective amount of a water-soluble pyrrolidone-containing polymer sufficient to form a protective film over the glass fiber.
Type:
Grant
Filed:
November 5, 1984
Date of Patent:
January 13, 1987
Assignee:
Owens-Corning Fiberglas Corporation
Inventors:
Donald J. Algrim, Donn R. Vermilion, Donald J. Hammond, Richard M. Haines