Patents Represented by Attorney, Agent or Law Firm Pepper Hamilton LLP
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Patent number: 7847130Abstract: An additive for improving the rate of catalysis in biphasic reaction systems is disclosed. The additive is an ionic molecule comprising an organic cation such as a heterocyclic compound or a quaternary ammonium or phosphonium cation, and an anion which may be organic or inorganic. A process for improved catalysis in an aqueous biphasic system wherein the catalyst is substantially dissolved in the aqueous phase and the substrate is substantially contained in the non-aqueous phase is also described. A suitable additive is 1-octyl-3-methylimidazolium halide. Examples of suitable catalytic reactions include the hydrogenation, hydrosilation, hydroboration, hydrovinylation, hydroformylation, oxidation and hydroxycarbonylation of alkenes, and Heck, Suzuki, Stille, and Sonigashira coupling.Type: GrantFiled: August 21, 2007Date of Patent: December 7, 2010Assignee: The University Court of the University of St. AndrewsInventors: David Cole-Hamilton, Simon Laurent Desset
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Patent number: 7845560Abstract: A method and apparatus for determining position and rotational orientation of an object within a predetermined area is disclosed. Position markers, encoded with their identity, are viewed with a camera, images are captured and processed, and the position and rotational orientation of the object are calculated. Three embodiments are disclosed; the first having a camera mounted on the movable object while position markers bearing linear bar codes are fixed in location, the second having a camera mounted on the movable object while position markers bearing two-dimensional bar codes are fixed in location, and the third having a position marker of either type affixed to the object while the camera is fixed in location.Type: GrantFiled: December 3, 2005Date of Patent: December 7, 2010Assignee: Sky-Trax IncorporatedInventors: David C. Emanuel, Larry G. Mahan, Richard H. Ungerbuehler
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Patent number: 7846723Abstract: The present invention provides methods of identifying and/or detecting anti-cancer agents. The present invention provides methods of identifying and/or detecting compounds that can activate PARP and/or induce necrosis. The present invention also provides for methods of treating cancer in an individual. The present invention also provides kits for identifying and/or detecting anti-cancer agents.Type: GrantFiled: September 15, 2008Date of Patent: December 7, 2010Assignee: The Trustees of the University of PennsylvaniaInventors: Craig B Thompson, Wei-Xing Zong
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Patent number: 7842684Abstract: The present invention provides 2-azetidinone derivatives, or pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof, comprising formula (I): wherein the substituents are as herein defined. The compounds possess cholesterol absorption inhibitory activity and are accordingly of value in the treatment of disease states associated with hyperlipidaemic conditions.Type: GrantFiled: April 25, 2007Date of Patent: November 30, 2010Assignee: AstraZeneca ABInventors: Malin Lemurell, Ingemar Starke
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Patent number: 7839521Abstract: A print system may include a job management server and a plurality of print stations. The job management server may receive, from a first network, a print stream that is representative of a document or graphic. The print stations may be located remotely from the job management server and may be in communication with the job management service via a second network. The job management server may deliver a copy of the print stream to one of the print stations for printing when a user who is authorized to access the print stream enters identifying information and selection data at the selected print station.Type: GrantFiled: August 9, 2005Date of Patent: November 23, 2010Assignee: Global Print Systems, Inc.Inventors: Bruce G. Bard, Jonathan Charles Dewees
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Patent number: 7838604Abstract: Disclosed is a new method and compositions from the method consisting of block copolycarbonate/phosphonates that exhibit an excellent combination of flame resistance, hydrolytic stability, high Tg, low melt viscosity, low color and high toughness. Also disclosed are polymer mixtures or blends comprised of these block copolycarbonate/phosphonate compositions and commodity and engineering plastics and articles produced therefrom. Further disclosed are articles of manufacture produced from these materials, such as fibers, films, coated substrates, moldings, foams, adhesives and fiber-reinforced articles, or any combination thereof.Type: GrantFiled: November 28, 2006Date of Patent: November 23, 2010Assignee: FRX Polymers, Inc.Inventor: Dieter Freitag
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Patent number: 7836884Abstract: A double-body therapeutics face and tracheostomy mask which functions as both a mask for the nose and mouth of a patient and a mask for the tracheostomy tube area of a patient is disclosed. The mask of the present invention serves as a means for delivering a gaseous medicament or a liquid, such as liquid medication, in the form of a fine spray or mist to the nose, mouth, and trachea of the patient simultaneously. The upper body (1) of the mask fits over the nose and mouth area of the patient and the lower body (5) of the mask fits a patient's tracheostomy tube area. The upper and lower mask bodies may be connected to one another and to a nebulizing apparatus (4) and adjustable-length delivery conduit (17). Therefore, the double-body therapeutics face and tracheostomy mask of the present invention may be adjusted to comfortably fit the face and trachea area of any sized patient.Type: GrantFiled: July 6, 2004Date of Patent: November 23, 2010Inventor: Vivian A. Wright
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Patent number: 7838789Abstract: A rocker switch (10) is provided with a mechanical switch unit consisting of a switch housing (11) made of plastic, a switching element (14) supported in spring-loaded manner on said switch housing so as to be capable of moving back and forth, and an actuating rocker (16) connected to the switching element (14), and also with limit-stop elements (48, 49, 51, 52) for limiting the actuating angle of the actuating rocker (16), and with an electrical switch unit. In order to obtain variable actuating angles and overcompression functions, the invention provides that the actuating rocker (16) is provided with an overcompression element (36) which in one or both of the actuating directions comes to be operationally connected to an overcompression stop (46, 47) on the switch housing (11) before the limit-stop elements (51, 52) come into operation.Type: GrantFiled: August 27, 2007Date of Patent: November 23, 2010Assignee: CoActive Technologies, Inc.Inventors: Michael Stoffers, Rainer Maurer, Uwe Gillmann
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Patent number: 7835922Abstract: A diagnostic system and method. In one embodiment, the invention is a diagnostic system comprising: a form comprising one or more diagnostic questions and one or more possible answers to each diagnostic question; a first overlay comprising one or more windows and one or more diagnostic fields, wherein when the first overlay is positioned over the form, the answers to the diagnostic questions that are indicative of the user having a first medical condition are visible through the windows of the first overlay; and wherein the one or more diagnostic fields contain criteria for diagnosing the user with the first medical condition based on the user's selection of answers on the form that are visible through the windows of the first overlay. In other embodiments, the invention is a computer-based version of the diagnostic system and a diagnostic method.Type: GrantFiled: June 29, 2005Date of Patent: November 16, 2010Assignee: AstraZeneca ABInventors: Fumihiko Sakai, Minoru Hosoda, Itsurou Kobayashi, Shinji Kutukake, Hareaki Yamamoto, Yoneyuki Kobayashi, Kouhei Yamashita, Hajime Baba, Masahiro Kitamura, Toshiyuki Shimizu, Yasuzumi Shimizu
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Patent number: 7834629Abstract: An MRI includes a cylindrical housing having a long axis in which a patient is positioned essentially in parallel with the long axis of the cylindrical housing. The MRI includes an electromagnetic receiver coil system positioned about a cylindrical housing and aligned with the long axis of the cylindrical housing. The MRI includes an electromagnetic imaging gradients coil system positioned about the cylindrical housing and aligned with the long axis of the cylindrical housing. The MRI includes a main magnet having its north pole and south pole positioned about the housing, which produces a magnetic field through the housing perpendicular to the long axis of the cylindrical housing. A method for examining a patient.Type: GrantFiled: September 11, 2008Date of Patent: November 16, 2010Assignee: Allegheny-Singer Research InstituteInventor: Mark Doyle
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Patent number: 7834625Abstract: An MRI to form an image of a patient includes at least one emitting coil which produces RF pulses and gradients. The MRI includes a controller in communication with the emitting coil for obtaining a steady-state image of the patient, where gradient areas balance to zero for each time repetition (TR) interval, and for causing the emitting coil to produce the RF pulses without interruption during the time repetition interval. The MRI includes at least one receiving coil in communication with the controller which receives the RF pulses and provides the RF pulses to the controller for the controller to obtain the image. A method to form an image of a patient with an MRI. A computer program embodied on a computer readable medium to form an image of a patient with an MRI.Type: GrantFiled: January 3, 2008Date of Patent: November 16, 2010Assignee: Allegheny-Singer Research InstituteInventors: Mark Doyle, Robert Biederman
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Patent number: 7829276Abstract: Screening and diagnostic reagents, kits and methods for stomach or esophageal cancer are disclosed. Compounds, compositions and methods of treating patients with stomach or esophageal cancer and for imaging stomach or esophageal tumors in vivo are disclosed. Compositions and methods for delivering active compounds such as drugs, gene therapeutics and antisense compounds to stomach or esophageal cells are disclosed. Vaccines compositions and methods of for treating and preventing stomach or esophageal cancer are disclosed.Type: GrantFiled: September 18, 2001Date of Patent: November 9, 2010Assignee: Thomas Jefferson UniversityInventors: Scott A. Waldman, Joshua M. Pearlman, Michael T. Barber, Stephanie Schulz, Scott J. Parkinson, Scott Prawer
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Patent number: 7824641Abstract: Provided herein is a new material, periodic mesoporous phosphorus-nitrogen compound, which may be used in a variety of emerging technologies. Its surface properties render it promising as a component in a variety of applications, including gas separation and purification systems in which waste gases such as SO2, SO3, or CO2 are separated from other gases. It may also be used as an interlayer dielectric in microelectronic chips. Its structure and composition are useful due to an advantageous and favorable combination of thermal stability, elastic modulus, and dielectric properties. The surface properties and the regularity of the pores furthermore provides utility as shape selective base catalysts. Protonated forms of the material are expected to be useful as a solid acid, and in applications such as acid catalysis. Additionally, because of the thermal behavior of the material, it is useful as “hard” template for other porous materials, without the need of an external reagent.Type: GrantFiled: May 23, 2008Date of Patent: November 2, 2010Assignee: Lehigh UniversityInventors: Kai Landskron, Paritosh Mohanty
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Patent number: 7820390Abstract: In vitro methods of determining whether or not an individual has metastasized colorectal cancer cells are disclosed. In vitro methods of determining whether or not tumor cells are colorectal in origin are disclosed. In vitro kits for practicing the methods of the invention and to reagents and compositions useful to practice the methods, for example as components in such in vitro kits of the invention are provided. Methods of and kits and compositions for analyzing tissue samples from the colon tissue to evaluate the extent of metastasis of colorectal tumor cells are disclosed.Type: GrantFiled: July 21, 2008Date of Patent: October 26, 2010Assignee: Thomas Jefferson UniversityInventor: Scott A Waldman
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Patent number: 7820153Abstract: cis-Jasmone has been discovered to be useful as a semiochemical that changes the behavior of insects and/or the physiology of plants. It has direct signalling roles with plant-feeding aphids, in attraction of aphid predators and parasitoids, and may act as an airborne signal inducing production of volatile plant semiochemicals, including the monoterpene (E)-?-ocimene, that stimulate foraging by parasitoids. It is an extremely benign compound having, to human beings, a pleasant aroma and gives a long-lasting effect after removal of the stimulus.Type: GrantFiled: November 24, 2004Date of Patent: October 26, 2010Assignee: Plant Bioscience LimitedInventors: Alastair James Hick, John Anthony Pickett, Lester John Wadhams, Johnathan Andrew Napier
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Patent number: 7816545Abstract: The present invention is directed to a process for the preparation of a diastereomerically pure dibenzoyl-L-tartrate salt of a compound of formula (III) and to products of said process.Type: GrantFiled: November 14, 2008Date of Patent: October 19, 2010Assignee: AstraZeneca ABInventors: Rhony Aufdenblatten, Martin Hans Bohlin, Laurent Ducry, Ulrika Lindblad, Mattias Magnusson
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Patent number: 7816486Abstract: Disclosed are branched polyphosphonates produced using a polycondensation process, that result in polyphosphonates having a Tg of at least 100° C., and which can be further processed to have improved hydrolytic stability compared to other polyphosphonates. The method and polyphosphonate compositions may be made from readily available starting materials providing lower cost fire retardant materials. Also disclosed are polymer compositions that comprise these branched polyphosphonates and at least one other polymer, wherein the resulting polymer compositions exhibit flame retardant properties.Type: GrantFiled: February 24, 2004Date of Patent: October 19, 2010Assignee: FRX Polymers, Inc.Inventors: Dieter Freitag, Michael A. Vinciguerra, Norman Rice, Richard Lusignea
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Patent number: 7815780Abstract: A device for removing mineral deposits from the electrode of a pool chlorinator cell, which has a housing with liquid inlet and outlet ports and in which the electrode is submerged, has: (a) a container having an opening, with this opening being affixed proximate an aperture that is placed in the housing, (b) an ultrasonic membrane which covers the aperture, (c) an ultrasonic transducer mounted in the container and coupled to the membrane in such a manner so as to cause specified, ultrasonic vibrations in the membrane and throughout the liquid contained in the housing, and (d) a frequency modulated power source that drives the transducer. In a preferred embodiment, this device is powered such that the energy projected to the electrodes is in range of 100 to 200 watts and the flux of energy supplied to the membrane is in the range of 4 to 25 watts per square inch of membrane surface area.Type: GrantFiled: October 4, 2004Date of Patent: October 19, 2010Assignee: Materials and Sensors Technologies, Inc.Inventor: B. Boro Djordjevic
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Patent number: 7817337Abstract: The present invention generally relates to a laminated image panel and a fabrication method thereof for projecting images projected from an image optical engine, on a screen by reflecting and/or transmitting the images. The laminated image panel in accordance with the present invention comprises front elements, rear elements disposed in opposition to the front elements, sealants for forming a predetermined cell by mutually bonding opposed rim parts of the front elements and the rear elements and for sealing the front and rear elements by separating the front elements from the rear elements at certain intervals, and a diffusing medium injected into the cell and uniformly diffusing the projection images in transparent and/or semitransparent state.Type: GrantFiled: January 6, 2006Date of Patent: October 19, 2010Inventor: Changmin Son
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Patent number: D627011Type: GrantFiled: May 28, 2009Date of Patent: November 9, 2010Inventor: Paul S. Potok