Patents Represented by Attorney, Agent or Law Firm Peter C. Richard - Justia Patents Search

Patents Represented by Attorney, Agent or Law Firm Peter C. Richard

N-[(substituted five-membered di- or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia

Patent number: 6492401

Abstract: NHE-1 inhibitors, methods of using such NHE-1 inhibitors and pharmaceutical compositions containing such NHE-1 inhibitors. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.

Type: Grant

Filed: August 18, 1999

Date of Patent: December 10, 2002

Assignee: Pfizer, Inc.

Inventors: Ernest S. Hamanaka, Angel Guzman-Perez, Roger B. Ruggeri, Ronald T. Webster, Christian J. Mularski