Patents Represented by Attorney, Agent or Law Firm Peter J. Manso
  • Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique urinary metabolite profiles
    Patent number: 6406715
    Abstract: Intermediate release nicotinic acid formulations having unique urinary metabolite profiles, which are suitable for oral administration once-a-day as a single dose during a 24 hour period for treating hyperlipidemia without causing drug-induced hepatotoxicity or drug-induced elevations in uric acid or glucose or both to levels that require the therapy to be discontinued, are disclosed.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: June 18, 2002
    Assignee: Kos Pharmaceuticals, Inc.
    Inventor: Eugenio A. Cefali
  • Transdermal delivery of the eutomer of a chiral drug
    Patent number: 5883115
    Abstract: A pharmaceutical composition of the eutomer of a chiral drug is disclosed whereby the eutomer has a clearance value greater than that of the racemic mixture of the chiral drug. The pharmaceutical compositions of the present invention allow the delivery of therapeutically effective levels of drugs at doses much lower than would be required when the drug is delivered by conventional injection methods.
    Type: Grant
    Filed: November 8, 1993
    Date of Patent: March 16, 1999
    Assignee: Pharmetrix Division Technical Chemicals & Products, Inc.
    Inventors: G. Carlo Santus, Richard W. Baker