Abstract: Circuits for detecting faults in variable resistive position feedback sensors common in the use of motion control systems, provide a filter coupled to an output signal of the variable resistive position sensor for processing the signal to detect noise indicative of intermittent faults. A memory stores occurrences of signals from the filter. The memory can activate an alarm which indicates that a failure is detected. The circuits are particularly applicable to medical imaging systems such as SPECT, PET or MRI systems which contain a multiplicity of moving components that require accurate motion control and positioning.

Abstract: A photo detector matrix may have a plurality of photo detectors arranged in a matrix each generating an output signal, and a plurality of wires coupled with the photo detectors, wherein a number of wires is less than a number of photo detectors and the plurality of photo detectors are assigned to the plurality of wires such that signals generated by the plurality of photo detectors encode a location of a light peak applied to the photo detector matrix.

Abstract: A method for correcting PET emission data for prompt gamma emission background components present in non-pure positron-emitting isotopes uses a two component fit of modeled scatter and modeled prompt gamma emission in the area of scatter tails in a normalized emission sinogram. The method allows a PET scan using non-standard PET isotopes to be quantitative and thus more clinically useful.

Abstract: A method for co-registering attenuation data of MR coils in a MR/PET imaging system with PET emission data includes computing a likelihood of PET emission data on a grid in a parameter space based on an algorithm, wherein the algorithm defines L(?, ?body, ?coils{p}) as a log-likelihood of measured PET data, where ? is an emitter distribution (image), ?body is a known linear attenuation coefficient (LAC) distribution of the body from MRI, ?coils is a linear attenuation coefficient map of MRI coils, and {p} is a set of parameters governing the position of each coil, wherein if ?coils is assumed, then ? can be reconstructed and forward projected and L can be computed. The method includes adjusting the estimated position of the MR coils to maximize the likelihood of emission data based on the computed L.

Abstract: The present invention provides a method for estimating crystal efficiency in a PET detector that takes axial compression into account. It does so via an iterative methodology in which a ?-map is first generated and then is used to obtain a solution for the equation L ? ( ? i ) = ? n ? N ? ? y n ? log ? ? i , j ? span ? ? g ij ? ? i ? ? j ? x ij - ? i , j ? span ? ? g ij ? ? i ? ? j ? x ij , wherein gij is a geometric factor for LOR(i,j), ?i and ?j are the efficiencies for crystal i and crystal j, and xij is the line integral of the source distribution along LOR(i,j). Once efficiencies are determined, they are used to calibrate the PET detector.

Abstract: A method and system for reconstructing PET image data from a cylindrical PET scanner by incorporation of axial system response. The method includes the steps of: assuming the decomposition of axial components into individual line-of-response (LOR) contributions, approximating each LOR spreading in image space as depth-independent, implementing each LOR response, combining the LORs to produce large span projection data, implementing the back projector as a transposed matrix, and assembling the LOR projections and spans for each azimuthal angle.

Abstract: A method for detecting Alzheimer's disease using positron emission tomography. A normal population mean is obtained using PET. The normal population mean is obtained through the assimilation of a number of normal brain scans. Non-AD images and AD images are compared to observe differences in the uptake of FDG. PET scan results are expressed as relative uptake intensities and indexed by Brodmann's areas. An image is tested by comparing the distance of each mean for each Brodmann's area from the normal distribution. A Receiver Operating Characteristic curve is plotted based on the variation of deviation for the total population of both normal and probable Alzheimer's brain images. Variations in FDG uptake in a brain image as compared to the normal distribution confirms the probability of AD.

Abstract: A system and method is provided for performing multimodal imaging of an object. The system and method includes performing spatio-temporal detection of transmission CT data of a fan X-ray beam, performing, and simultaneously with the spatio-temporal detection of transmission CT data, spatio-temporal detection of emission nuclear imaging data emitted from the object with a propagation direction across the propagation direction of the fan X-ray beam. The system and method further includes identifying at least two zones in the object based on the transmission CT data, reconstructing an image object from the emission nuclear imaging data under the constraint that respective portions of detected nuclear events are associated with selected zones, and outputting data representative of the image object.

Abstract: An apparatus and method is provided for pulling a crystal seed from melt for growing a single crystal. The method includes the steps of providing a crucible and providing within the crucible an outer container, and providing coaxially within the outer container an inner container. A protruding portion of the inner container protrudes downward relative to the outer container for containing melt, the inner and outer containers defining an annular channel therebetween which has a bottom wall and contains introduced charge feed. The method further includes the steps of providing for allowing fluid communication between the annular channel and the inner container, delivering charge feed into the annular channel, and generating heat from within the annular channel for preventing the formation of a condensate of the charge feed within the annular channel.

Abstract: A method for determining quality of sinograms produced by a medical imaging device. The method may include placing a uniform phantom object in the field of view of the medical imaging device; acquiring one or more phantom sinograms of the uniform phantom object; establish a set of parameters for the acquired one or more phantom sinograms; and determine, based on pre-set ranges of the parameters, the quality of sinograms produced by the medical imaging device. The parameters may be one or more parameters of a group of parameters consisting of block uniformity, block efficiency, randoms rate, scanner efficiency, and scatter ratio.

Abstract: A method and device for reducing positron emitter isotope labeled CO2 to positron emitter isotope labeled CO generally includes introducing a volume of positron emitter isotope labeled CO2 into a first heated reaction vessel comprising a metal oxide, such as Iron (II) Oxide such that the CO2 is reduced to CO upon contact with the Iron (II) Oxide. The volume is then transferred to a second reaction vessel to remove any un-reacted CO2, preferably, via a soda-lime trap. The volume is then transferred to a target, e.g., a storage vessel or subject. The CO2 includes one of [11C] or [15O]. The first reaction vessel is, preferably, heated to a temperature of between 900 and 1000° C., and more preferably, to between 925 and 975° C., and even more preferably, to approximately 950° C. Preferably, the Iron (II) Oxide powdered and has a particle size of about ?10 mesh.

Abstract: A method for interpolating at least one oblique line of response ray representing nuclear image projection data through a rectangular volume and a system for using the method. The method consists of steps of interpolating all the direct rays in a rectangular volume, making a projected ray by projecting the oblique ray onto a surface of the rectangular volume, matching the projected ray to a coinciding interpolated direct ray, shearing the rectangular volume to match the projected ray, and interpolating the oblique ray in the sheared volume.

Abstract: A method for improving clinical data quality in Positron Emission Tomography (PET). The method provides for the processing of PET data to accurately and efficiently determine a data single-to-noise ratio (SNR) corresponding to each individual clinical patient scan, as a function of a singles rate in a PET scanner. The method relates an injected dose to the singles rate to determine SNR(Dinj),and provides an accurate estimate of a quantity proportional to SNR, similar in function to the SNR(Dinj). Knowledge of SNR(Dinj) permits determination of peak SNR, optimal dose, SNR deficit, dose deficit, and differential dose benefit. The patient dose is fractionated, with a small calibration dose given initially. After a short uptake, the patient is pre-scanned to determine T, S, and R. An optimal does is then determined and the remainder injected.

Abstract: Axial rebinning methods are provided for 3D time-of-flight (TOF) positron emission tomography (PET), based on 2D data rebinning. Rebinning is performed separately for each axial plane parallel to the axis of the PET scanner. An analytical approach is provided that is based on a consistency condition for TOF-PET data with a gaussian profile. A fully discrete approach is also provided, wherein each 2D TOF-PET data is calculated as a linear combination of 3D TOF-PET data having the same sinogram coordinates s and ?.

Abstract: An apparatus and method for nuclear medical imaging (e.g., SPECT imaging) using cone-beam or multifocal collimators is disclosed. According to the embodiment of the invention, the detector/collimator is tilted in a fore-aft direction, with the tilt angle varying as a function of the orbital position of the detector assembly. The patient pallet may also be moved longitudinally as a function of the tilt angle (i.e., as a function of the orbital position) for optimal image quality.

Abstract: The present invention provides a system and method for a system for accommodating a solid target in an accelerator. The system and method includes a target changer having at least one port for accommodating the solid target, an insert for receiving the solid target in the target changer, a piston for providing a vacuum and a cooling system for the solid target, a cylinder for displacing the piston in one of three positions; and a bracket for securing the insert, piston and cylinder to the target changer.

Abstract: An accessory for a patient's use during a medical procedure is disclosed. The accessory includes a pillow that has an inner material and an outer material. The pillow includes a head support, at least one shoulder support and at least one hand support. The head support has a right side, a left side and a top side. The shoulder support is disposed adjacent the right side and/or the left side of the head support. The hand support is disposed adjacent the top side of the head support. The inner material of the pillow is made of a substantially rigid material. The outer material of the pillow is made of a substantially soft material.

Abstract: A scanning device and a drive system for a scanning device having a first detector and a second detector are provided, which include a base and a mounting plate movably supported by the base. The mounting plate is configured to movably support the first detector and the second detector. The drive system also includes a drive device configured to move the mounting plate with respect to the base, and a linear actuator configured to move the second detector with respect to the mounting plate.

Abstract: A method and system of volume deformation, including accessing a tree structure for a set of deformation maps. The tree structure is traversed for each voxel in an original volume and each voxel is transformed according to each deformation map corresponding to a node of the tree structure until the entire original volume is deformed into reference volume space. Also, a method and system of generating an ordered map tree structure, including identifying a root node of a bounding box, the bounding box being a union of the root node's descendants. Child nodes are identified for each node, the child nodes being ordered so that a left child is applied before a corresponding right child, wherein each child node contains a deformation map and a corresponding bounding box. Each path originating from the root node corresponds to a complete deformation map sequence, and when a portion of two deformation maps overlap, the deformation map having a lower priority is a child of the deformation map having a higher priority.

Abstract: A method for performing accurate iterative reconstruction of three dimensional image data sets based on Approximate Discrete Radon Transformation (ADRT) using two dimensional linograms for each of a plurality of defined planes tilted from the (x, y, 0) plane by a tilt angle and orientation angle. Image data is arranged with respect to the defined tilted planes ADRT and its inverse are implemented to provide exactly matched forward and backward projectors suitable for the Maximum-Likelihood Expectation-Maximization (ML-EM) reconstruction in PET. An EM reconstruction algorithm is accomplished by initializing an estimation image.