Patents Represented by Attorney, Agent or Law Firm Pharmacia & Upjohn Attorney
  • Methods of identifying anti-viral agents
    Patent number: 6641994
    Abstract: The invention provides methods to identify specific inhibitors of HPV E7 binding to CDK2 complex and methods to identify specific inhibitors of E7-induced CDK2 kinase activity. Specific inhibitors identified by the methods, compositions comprising the specific inhibitors, and methods of treatment using the compounds are also provided.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: November 4, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Christopher Fisher, Wanxia He
  • Treatments for nervous disorders
    Patent number: 6586427
    Abstract: This patent application describes the treatment of Addictive disorders, Psychoactive Substance Use disorders, Intoxication disorders, Inhalation disorders, Alcohol addiction, Tobacco addiction and or Nicotine addiction; and Attention Deficit Hyperactivity Disorder (ADHD); comprising administering a therapeutically effective, nontoxic dose of Reboxetine and derivatives and or pharmaceutically acceptable salts thereof to a patient.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: July 1, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Fred Hassan, John Michael McCall, Duncan Paul Taylor, Philip F. Von Voigtlander, Erik Ho Fong Wong
  • Aspartyl protease 2 (Asp2) antisense oligonucleotides
    Patent number: 6500667
    Abstract: The present invention provides the enzyme and enzymatic procedures for cleaving the &bgr; secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: December 31, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Mark E. Gurney, Michael J. Bienkowski, Robert L. Heinrikson, Luis A. Parodi, Riqiang Yan
  • Anti-bacterial methods and materials
    Patent number: 6485899
    Abstract: Staphylococcus aureus virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel S. aureus mutants useful in vaccines.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: November 26, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: David Holden, Ji Min Mei
  • Anti-bacterial methods and materials
    Patent number: 6455323
    Abstract: Staphylococcus aureus virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel S. aureus mutants useful in vaccines.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: September 24, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: David Holden, Ji Min Mei