Patents Represented by Attorney, Agent or Law Firm Phil L. McGarrigle
  • Nucleic acid labeling compounds
    Patent number: 6596856
    Abstract: Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: July 22, 2003
    Assignee: Affymetrix, Inc.
    Inventors: Glenn McGall, Anthony D. Barone
  • Methods for testing oligonucleotide arrays
    Patent number: 6576425
    Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acids.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: June 10, 2003
    Assignee: Affymetrix, Inc.
    Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee