Patents Represented by Attorney, Agent or Law Firm Philip L. McGarrigle, Esq.
  • Methods for polymer synthesis
    Patent number: 6747143
    Abstract: A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group, is provided to the substrate to bind at the selected areas. The process is repeated using a variety of monomers such as amino acids until sequences of a desired length are obtained. Detection methods and apparatus are also disclosed.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: June 8, 2004
    Assignee: Affymetrix, Inc.
    Inventors: Lubert Stryer, Stephen P. A. Fodor, J. Leighton Read, Michael C. Pirrung
  • Photolithographic and other means for manufacturing arrays
    Patent number: 6416952
    Abstract: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 9, 2002
    Assignee: Affymetrix, Inc.
    Inventors: Michael C. Pirrung, Lubert Stryer, Stephen P. A. Fodor, J. Leighton Read