Patents Represented by Attorney, Agent or Law Firm Phillip B.C. Jones
  • Antibodies that bind human Zven1
    Patent number: 6828425
    Abstract: The present invention provides two members of a new family of human proteins, designated as “Zven.” The Zven1 gene, which resides in human chromosome 3p21.1-3p14.3, is expressed in testicular tissue and peripheral blood lymphocytes.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: December 7, 2004
    Assignee: ZymoGenetics, Inc.
    Inventors: Paul O. Sheppard, Paul D. Bishop
  • Methods for generating a continuous nucleotide sequence from noncontiguous nucleotide sequences
    Patent number: 6730500
    Abstract: The increased use of nucleotide sequence data mining techniques has amplified the demand for efficient methods of producing recombinant proteins in host cells. New genes identified from genomic sequences may lack an identified source for obtaining an mRNA template to produce cDNA. A strategy is provided for generating nucleic acid molecules comprising a continuous amino acid-encoding sequence using a genomic template that contains non-continuous amino acid-encoding sequences.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: May 4, 2004
    Assignee: ZymoGenetics, Inc.
    Inventor: Si Lok
  • Zcys6: a member of the cystatin superfamily
    Patent number: 6703224
    Abstract: The cystatin superfamily includes inhibitors of cysteine proteinases, which function in a protective role with regard to various pathological actions of endogenous proteinases. Zcys6 is a new member of this superfamily.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: March 9, 2004
    Assignee: ZymoGenetics, Inc.
    Inventors: Scott R. Presnell, Zeren Gao
  • Interferon-epsilon
    Patent number: 6544505
    Abstract: Interferons represent an important class of biopharmaceutical products, which have a proven track record in the treatment of a variety of medical conditions, including the treatment of certain autoimmune diseases, the treatment of particular cancers, and the enhancement of the immune response against infectious agents. To date, four types of interferons have been found in humans: interferon-&agr;, interferon-&bgr;, interferon-&ggr;, and interferon-&ohgr;. The present invention provides new forms of human and murine interferon, “interferon-&egr;,” which have applications in diagnosis and therapy.
    Type: Grant
    Filed: October 4, 2001
    Date of Patent: April 8, 2003
    Assignee: ZymoGenetics, Inc.
    Inventors: Darrell C. Conklin, Francis J. Grant, Mark W. Rixon, Wayne Kindsvogel
  • Nucleic acid molecules that encodes human Zven1
    Patent number: 6485938
    Abstract: The present invention provides two members of a new family of human proteins, designated as “Zven.” The Zven1 gene, which resides in human chromosome 3p21.1-3p14.3, is expressed in testicular tissue and peripheral blood lymphocytes.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: November 26, 2002
    Assignee: ZymoGenetics, Inc.
    Inventors: Paul O. Sheppard, Paul D. Bishop
  • Method for producing proteins in transformed Pichia
    Patent number: 6258559
    Abstract: Methylotrophic yeasts are useful hosts for the production of commercially valuable recombinant proteins. However, the development of large-scale cultures of recombinant methylotrophic yeasts has been hindered by the formation of precipitation in culture media. A new soluble minimal medium overcomes this problem. Moreover, new feeding schemes provide cultures of high biomass, which produce biologically active recombinant protein.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: July 10, 2001
    Assignee: ZymoGenetics, Inc.
    Inventor: Bruce L. Zamost