Abstract: The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Fusarium solani infection (the causative agent of sudden death syndrome or SDS). The methods use molecular genetic markers to identify, select and/or construct disease-tolerant plants or identify and counterselect disease-susceptible plants. Soybean plants that display tolerance or improved tolerance to Fusarium solani infection that are generated by the methods of the invention are also a feature of the invention.

Abstract: Oleosin- and steroleosin-encoding polynucleotides from coffee plants are disclosed. Also disclosed are promoter sequences from coffee oleosin genes, and methods for using these polynucleotides and promoters for gene regulation and manipulation of flavor, aroma and other features of coffee beans.

Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.

Abstract: The present invention concerns ten novel variants of alternative splicing of the hormonal imbalance related genes.

Abstract: A tool assembly comprising a tool having a distal end and a proximal end having a protrusion thereon; and a device coupled with the proximal end of the tool, wherein the device is capable of accommodating a tool and has a compartment for storing various items.

Abstract: Applicants have used protein design to develop novel functional protein architectures, termed protein kinase-inducible domains, whose structures are dependent on phosphorylation by specific protein kinases or are dependent on dephosphorylation by specific protein phosphatases. Applicants have designed kinase-inducible domains based on a modular architecture, which allows kinase-inducible domains to be responsive to any specific serine-threonine kinases. Kinase-inducible domains can consist of canonical amino acids, allowing their use as expressible tags of protein kinase activity.

Abstract: Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.

Abstract: The present disclosure relates, in one aspect, to use of ghrelin splice variant or an analogue thereof for the preparation of a medicament for one or more of: treatment and/or prevention of loss of body weight and body fat, prophylaxis or treatment of cachexia, stimulation of appetite, stimulation of food intake, stimulation of weight gain, or increasing body fat mass, or increasing body lean mass. Another aspect relates to the use of a ghrelin splice variant-like compound for the preparation of a medicament for the prophylaxis or treatment of cancer cachexia in an individual in need of such treatment. Another aspect relates to the use of a ghrelin splice variant-like compound for the preparation of a medicament for prophylaxis or treatment of cachexia in an individual by administering a subcutaneous dosage of said medicament to the individual.

Abstract: Disclosed herein are polynucleotides encoding a chimeric C—C chemokine receptor 2B, the encoded polypeptides thereof, and methods of making and using said polynucleotides and polypeptides.

Abstract: Methods of producing lung surfactant formulations through solvent dissolution and lyophilization are described as well as surfactant formulations derived therefrom. Methods of treating respiratory distress dysfunction are also provided.

Abstract: Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.

Abstract: Regimens for the therapeutic or prophylactic administration of pulmonary surfactant to infants exhibiting or at risk of developing bronchopulmonary dysplasia are disclosed.

Abstract: Disclosed herein are nucleic acid and polypeptide sequences of a novel rat voltage-gated potassium channel, KCNQ5. Also disclosed herein are methods related to the use of the aforementioned potassium channel.

Abstract: The invention provides a method of preventing contamination of a canvas of a paper machine, whereby antifouling effect on the canvas can always be maintained and precise drying efficiency is ensured. With the method of preventing contamination of the canvas for pressing a paper strip against the surface of drum-dryers used for drying the paper strip in a paper machine, a predetermined amount of a surface treatment agent P is continuously supplied to the surface of the canvases C2, C3, facing the paper strip, in a stage of operation prior to the paper strip being pressed into contact with the canvases C2, C3 as well as the drum-dryers C1, while the paper strip is being fed by operation of the paper machine.

Abstract: This invention relates to a novel PTH gene. The invention further relates to methods of screening, diagnosis and development of therapies for bone related disorders.

Abstract: The present invention concerns a protein produced from an alternative splice form of the human Ghrelin gene, an obesity and/or diabetes related gene.

Abstract: The invention provides a method of preventing contamination of a dryer of a paper machine so that predetermined effects of contamination prevention over the long term can always be ensured while maintaining satisfactory drying efficiency. With the method of preventing contamination of the surface of the drum dryer used in a paper machine, a predetermined amount of a surface treatment agent P is continuously supplied to the surface of the drum dryer C1 in rotation, facing a paper strip W, while the paper strip is being fed by the paper machine in operation.

Abstract: The present invention provides a flexible mounting for securing at least one evacuation member to a fitment for use in a collapsible bag. The mounting comprises a peripheral ring adapted to fit within a spout of the fitment, a central member to which the at least one evacuation member is secured and a plurality of spring members extending between the peripheral ring and the central member, the spring members supporting the central member while permitting the central member to be displaced relative to the peripheral ring.

Abstract: A single service package coupling and valve includes a fitment having a spout and a sliding tubular valve member mounted therein for receiving a cooperating dispensing connector of a liquid distributing and dispensing system, and an external adapter ring designed to cooperate with the mounting mechanisms of a plurality of conventional commercially available dispensing connectors. An internal adapter sleeve is mounted with in the sliding tubular valve member to provide a tight seal with any of the conventional dispensing connectors. The external adapter ring is provided with a pair of radially extending flanges adapted to accept and position different dispensing connectors. At least one of the radially extending flanges is provided with at least two wings to engage a threaded mounting collar of a service line connector.