Abstract: Towelette dispenser and vapor impervious pouch containing a roll or web of absorbent material, such as non-woven fibrous towelettes pre-moistened with a chemical-containing aqueous or other fluid solution. The pouch is sealed before use to prevent the loss of moisture from the pre-moistened towelette roll and is opened at the point of, and at the time of, first use. A double lid is adapted to provide moisture seal between usages of the pre-moistened towelette, while reducing dehydration of the opened towelette pouch within the dispenser. Feed slit adaptations in the lid provide for selective tearability of individual towelette portions from the roll. The dispenser is adapted to provide a low center of gravity, and the base of the dispenser can cooperatingly engage a wall-type holder. The towelette roll contains a leader adapted for ease of feeding through the feed slot upon first use.