Patents Represented by Attorney Prabodh I. Almaula
  • Patent number: 4255152
    Abstract: A batchwise process for dyeing hydrophobic fibres at 110.degree. C. to 135.degree. C. with a disperse dye in the presence of an adduct of an average of 1 to 4 molar proportions of ethylene oxide, propylene oxide or styrene oxide or a combination of these oxides with 1 molar proportion of a phenol compound having the formula ##STR1## in which n is a number from 1 to 4,R.sub.1 is hydrogen, chlorine an alkyl group with 1 to 8 carbon atoms, an alkoxy group with 1 to 8 carbon atoms or an alkenyl group with 2 to 8 carbon atoms.R.sub.
    Type: Grant
    Filed: September 5, 1978
    Date of Patent: March 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Brian Hewitt, Cyril Hobday, James Jack, John F. E. Keenan
  • Patent number: 4254032
    Abstract: Carbazolylmethane compounds of the formula ##STR1## wherein one of Y.sub.1, Y.sub.2 and Q represents a 3-carbazolyl radical of the formula ##STR2## and each of the other two independently represents an amino-substituted phenyl radical of the formula ##STR3## a 3-indolyl radical of the formula ##STR4## a 3-carbazolyl radical of the formula ##STR5## or a 3-carbazolyl radical of the formula (1a), and Q also represents hydrogen, alkyl of 1 to 12 carbon atoms, alkenyl containing not more than 12 carbon atoms, aryl, aralkyl or a further heterocyclic radical, while each of X.sub.1 and X.sub.2 independently represents hydrogen, alkyl containing not more than 12 carbon atoms which is unsubstituted or substituted by halogen, hydroxyl, cyano or lower alkoxy, or represents cycloalkyl, phenyl, benzyl, or phenyl or benzyl which is substituted by halogen, lower alkyl or lower alkoxy, or X.sub.1 and X.sub.2 together with the nitrogen atom to which they are attached represent a 5- or 6-membered heterocyclic radical, X.sub.
    Type: Grant
    Filed: April 12, 1979
    Date of Patent: March 3, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Jean C. Petitpierre, Peter Burri
  • Patent number: 4252975
    Abstract: A 3-indolyl-3-bis-aminophenyl-phthalide compound of the formula ##STR1## wherein R.sub.1 represents alkyl which has at most 12 carbon atoms and is unsubstituted or substituted by halogen, hydroxyl, cyano or lower alkoxy, cycloalkyl, or unsubstituted or substituted phenyl or benzyl wherein the substituents are halogen, nitro, lower alkyl or lower alkoxy,R.sub.2 represents hydrogen, alkyl which has at most 12 carbon atoms and is unsubstituted or substituted by halogen, hydroxyl, cyano or lower alkoxy, cycloalkyl, or benzyl which is unsubstituted or substituted by halogen, nitro, lower alkyl or lower alkoxy, orR.sub.1 and R.sub.2 together with the nitrogen atom linking them represent a 5- or 6-membered heterocyclic radical,X.sub.1 and X.sub.2 independently of one another represent hydrogen, lower alkyl, cycloalkyl, benzyl which is unsubstituted or substituted by halogen, nitro, lower alkyl or lower alkoxy, or acyl having 1 to 8 carbon atoms, and X.sub.
    Type: Grant
    Filed: December 21, 1978
    Date of Patent: February 24, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Jean C. Petitpierre, Robert Garner
  • Patent number: 4251542
    Abstract: The present invention provides new imino compounds having the formula I ##STR1## wherein R.sub.1 represents an aliphatic or cycloaliphatic hydrocarbon radical, unsubstituted or substituted phenyl, or phenyl-lower alkyl or diphenyl-lower alkyl, which radicals are unsubstituted or substituted in the phenyl ring(s),R.sub.2 represents unsubstituted or substituted phenyl, unsubstituted or substituted monocyclic heteroaryl or lower alkyl,R.sub.3 represents hydrogen, lower alkyl, a carbonyl group linked with R.sub.2 to form a five-membered ring, or the group R.sub.6 --CO wherein R.sub.6 represents lower alkyl or unsubstituted or substituted phenyl,R.sub.4 represents, if present, hydrogen or lower alkyl which is independent or is linked with R.sub.1 to form a five- to seven-membered ring which can contain as ring members two aromatic ring carbon atoms of an unsubstituted or substituted phenyl or phenyl-lower-alkyl radical R.sub.
    Type: Grant
    Filed: September 20, 1978
    Date of Patent: February 17, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Atso Ilvespaa, Walter Fuhrer
  • Patent number: 4251517
    Abstract: The antibiotics Papulacandin A and Papulacandin B are etherified at the phenolic groups in positions 10 and/or 12 by introducing a group--CH.sub.2 --Kwherein K is a hydrocarbon radical which is either unsaturated and aliphatic, or it is saturated or unsaturated and substituted by cyclic hydrocarbons, such as aromatic or heterocyclic ones, or by functional groups, such as halogens, carboxyl groups, carboxyl ester or amide groups. These ethers are characterized by a good antifungal action e.g. against Candida albicans and also by an antifiral action.
    Type: Grant
    Filed: June 27, 1979
    Date of Patent: February 17, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Peter Traxler
  • Patent number: 4250317
    Abstract: Novel benzofuranyl benzimidazoles of the formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkenyloxy or cycloalkloxy radical, an unsubstituted or substituted alkoxy, phenylalkoxy or phenoxy radical, each ofR.sub.2 and R.sub.3 independently represents a hydrogen atom, an alkyl or alkoxy radical, a halogen atom, or, if R.sub.1 represents hydrogen, together in the ortho-position to each other they represent a radical of the formula --CH.dbd.CH--CH.dbd.CH--, --O--CH.sub.2 --O-- or --O--CH.sub.2 --CH.sub.2 --O--,R.sub.4 represents a hydrogen atom, an alkyl, alkoxy or phenyl radical,R.sub.5 represents a sulpho or carboxyl group or the functional derivatives thereof including the cyano group or the trifluoromethyl group,R.sub.6 represents a hydrogen or halogen atom, an alkyl or alkoxy radical,R.sub.7 represents a cycloalkyl, alkenyl, or unsubstituted or substituted alkyl, phenyl or phenylalkyl radical, or, if n is O, also represents a hydrogen atom,R.sub.
    Type: Grant
    Filed: December 21, 1978
    Date of Patent: February 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans R. Meyer, Kurt Weber
  • Patent number: 4248868
    Abstract: The invention comprises carbonylmethyl derivatives of the formula IA and corresponding carbonylmethylene derivatives of the formula IB ##STR1## in which R.sub.1.sup.a represents a member of the group comrising hydrogen and an acyl radical of the formula AR.sub.a --C(R.sub.b)(R.sub.c)--C(.dbd.O)-- (A)in which R.sub.a represents a member of the group comprising optionally substituted phenyl, thienyl, furyl, cyclohexadienyl and cyclohexenyl, R.sub.b represents hydrogen and R.sub.c represents a member of the group comprising hydrogen, optionally protected hydroxyl, optionally protected amino and phenyl-lower protected sulpho, or in which R.sub.a represents a member of the group comprising cyano, optionally substituted phenoxy, pyridylthio, and tetrazolyl, and R.sub.b and R.sub.c each represent hydrogen, or in which R.sub.a represents a member of the group comprising phenyl, thienyl, furyl, and R.sub.b and R.sub.
    Type: Grant
    Filed: February 23, 1979
    Date of Patent: February 3, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Riccardo Scartazzini, Hans Bickel
  • Patent number: 4249027
    Abstract: According to the present invention, 5-substituted resorcinols of the formula I ##STR1## wherein R.sub.1 represents a hydrocarbon radical, optionally unsubstituted or substituted by inert substituents, are prepared by reacting a carboxylic acid ester of the formula IIR.sub.1 --C.tbd.C--CO--O--R.sub.2 (II)wherein R.sub.2 represents a non-aromatically bound lower hydrocarbon radical, in the presence of an alkaline condensation agent, with a diester of 3-oxoglutaric acid of the formula IIIR.sub.3 --O--CO--CH.sub.2 --CO--CH.sub.2 --CO--O--R.sub.4 (III)wherein R.sub.3 and R.sub.4 represent non-aromatically bound lower hydrocarbon radicals; hydrolyzing the resulting dihydroxyisophthalic acid acid ester of the formula IV ##STR2## and decarboxylating the hydrolyzed product, a specific embodiment is the preparation of 5-pentylresorcinol.
    Type: Grant
    Filed: November 1, 1976
    Date of Patent: February 3, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Jacques Gosteli
  • Patent number: 4247293
    Abstract: The invention relates to sulphonated, aromatic reaction products as agents for tanning hides and leather. They are obtained by reacting a sulphonation product, which is previously formed from a diphenyl ether, a phenol and a sulphonating agent, with formaldehyde, with a reaction mixture of an aminoplast-forming agent and formaldehyde or with an aminoplast precondensate.
    Type: Grant
    Filed: February 12, 1979
    Date of Patent: January 27, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Albert Wurmli
  • Patent number: 4245990
    Abstract: A process for producing solutions of salts of water-soluble carboxylic acids of cationic dyes or optical brighteners, the solutions of cationic dye salts or brighteners salts which are obtained by this process and which are miscible with water in any proportion, and the use of these solutions for preparing dye liquors and printing pastes for dyeing, optical brightening and printing of, in particular, synthetic textile materials, which process comprises reacting the halide of a cationic dye or brighteners, in an aqueous or anhydrous medium, with at least one water-soluble carboxylic acid in the presence of an epoxide compound having a minimum of 13 carbon atoms.
    Type: Grant
    Filed: December 21, 1978
    Date of Patent: January 20, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Peter Loew, Walter Lang
  • Patent number: 4246269
    Abstract: The present invention provides new derivatives of perhydro-aza-heterocycles of the formula ##STR1## in which X is the oxo radical or hydrogen and the radical OR.sub.1, in which R.sub.1 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, a substituted or unsubstituted araliphatic hydrocarbon radical or a substituted or unsubstituted aromatic hydrocarbon radical or an acyl radical, R.sub.2 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, Y is oxygen or sulphur, n.sub.1 and n.sub.2 each are values of 1 to 3, n.sub.1 +n.sub.2 being at most four, and Ar is a substituted or unsubstituted aromatic hydrocarbon radical, and the acid addition salts, in particular the pharmaceutically acceptable acid addition salts thereof. These new substances possess valuable pharmacological properties, in particular antidepressant activity, and can be used for the treatment of mental depressions.
    Type: Grant
    Filed: April 5, 1979
    Date of Patent: January 20, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Romeo Paioni
  • Patent number: 4245007
    Abstract: New 1,4-bis-[azol-2'-yl]-naphthalene compounds, a process for their preparation as well as a process for optically brightening organic materials on using said compounds are disclosed.
    Type: Grant
    Filed: August 1, 1978
    Date of Patent: January 13, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Leonardo Guglielmetti
  • Patent number: 4244691
    Abstract: The invention relates to novel, water-soluble anthraquinone dyes which, in the form of the free acid, have the formula I ##STR1## in which X is halogen, R.sub.1 is an unbranched or branched alkyl radical having 4 to 8 carbon atoms, R.sub.2 and R.sub.3 independently of one another are an unbranched or branched alkyl radical having 1 to 4 carbon atoms, R.sub.4 is hydrogen, an unbranched or branched alkyl radical having 1 to 4 carbon atoms, a free or acylated amino group or a fibre-reactive radical bonded via an amino group, R.sub.5 is hydrogen or an unbranched or branched alkyl radical having 1 to 4 carbon atoms and R.sub.6 and R.sub.7 independently of one another are hydrogen, an unbranched or branched alkyl radical having 1-4 carbon atoms, a --SO.sub.3 H group, halogen or a radical of the formula --CH.sub.
    Type: Grant
    Filed: November 16, 1979
    Date of Patent: January 13, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Jean-Marie Adam
  • Patent number: 4243809
    Abstract: The invention provides compounds of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 independently is a hydrogen atom or a substituted or unsubstituted alkyl or aryl radical, R.sub.3 is a hydrogen atom or the carbamoyl radical, and X is a substituted or unsubstituted alkyl or alkenyl radical. A process for preparing these compounds is also disclosed.
    Type: Grant
    Filed: October 26, 1978
    Date of Patent: January 6, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Karl Seitz
  • Patent number: 4243418
    Abstract: A process for fireproofing polyester fibers is provided in which a substituted mono- or disulphurylamide of the formula ##STR1## wherein n is 1 or 2, R are aromatic, cycloaliphatic or aliphatic radicals or hydrogen and A is alkylene or an ammonium salt of such a sulphurylamide is applied to the fiber material which is then dried and subjected to a heat treatment. The sulphurylamide may also be applied in the presence of a dispersant, a protective colloid and/or water. The composition of matter for performing this process is also provided.
    Type: Grant
    Filed: September 21, 1978
    Date of Patent: January 6, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Hermann Nachbur, Armin Hiestand, Peter Rohringer
  • Patent number: 4241075
    Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 and R.sub.2 are each chlorine or methyl, R.sub.3 is hydrogen or C.sub.1 -C.sub.4 -alkyl and R.sub.4 is C.sub.1 -C.sub.6 -alkyl optionally substituted by cyano or phenyl optionally substituted by halogen and/or methyl are novel and are pesticidally in particular acaricidally active.
    Type: Grant
    Filed: September 17, 1979
    Date of Patent: December 23, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Manfred Boger, Jozef Drabek, Gunter Mattern, Walter Traber
  • Patent number: 4238328
    Abstract: A process for removing heavy-metal ions from aqueous solutions, particularly from effluents. The process comprises bringing the aqueous solutions into contact with a water-insoluble adsorbent which has been produced from:(a) a basic polynitrogen compound capable of being acylated;(2) an aliphatic or araliphatic carboxylic acid containing mobile substituents or a multiple bond capable of undergoing addition; and(3) a crosslinking compound which contains at least two reactive substituents and which is different from component (2).
    Type: Grant
    Filed: February 14, 1979
    Date of Patent: December 9, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Quentin Bowes, Rudolf F. Wurster
  • Patent number: 4238481
    Abstract: Sulphur-free cyclopeptides with somatostatin-analogous aminoacid partial sequences, of the formula ##STR1## in which R is Asn, Ala or de-R, trp is D-Trp or L-Trp, which can be substituted in the benzene ring by halogen atoms or nitro groups, W is a free or etherified hydroxyl group or halogen atom present as a substituent on the benzene ring of the L-phenylalanine radical, or is hydrogen, X is the radical of an .omega.-amino-lower alkane-(mono or di)-carboxylic acid or de-X and Y is the radical of an .omega.-amino-lower alkane-(mono or di)-carboxylic acid or de-Y, and also acid addition salts and complexes thereof have biological properties similar to those of somatostatin and can be used, especially in the form of pharmaceutical preparations, for the treatment of excessive secretion of somatotropin, insulin and/or glucagon. The compounds according to the invention are obtained by cyclising a corresponding linear peptide compound in which the .epsilon.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: December 9, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans Rink, Bruno Kamber, Peter Sieber
  • Patent number: 4238504
    Abstract: Cyclopropanecarboxylic acid-phenoxy-.alpha.-vinyl-benzyl esters of the formula ##STR1## in which Y is chlorine or bromine, and R.sub.1 is --CH.dbd.CH.sub.2 or ##STR2## processes for producing them, and their use in combating pests.
    Type: Grant
    Filed: June 22, 1979
    Date of Patent: December 9, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Jozef Drabek, Peter Ackermann, Saleem Farooq, Laurenz Gsell, Odd Kristiansen
  • Patent number: 4237179
    Abstract: A process is provided for flameproofing cellulose containing fiber material which is dyed with copper-complex azo dyes. In this process the fiber material is heated with an aqueous composition containing(a) a dialkylated phosphono-propionic acid amide or its N-methylolated derivate(b) an alkanolamine such as a 2-amino-2-alkyl-1-alkanol(c) a water-soluble copper salt such as copper (II) chloride or sulphate(d) optionally an aminoplast precondensate or an etherified aminoplast pre-condensate such as methylolated or melamines or their alkyl ethers.The treated fiber material is dryed (e.g. up to 120.degree. C.) and then subjected to a heat treatment at e.g. 140.degree. to 200.degree. C.
    Type: Grant
    Filed: August 15, 1977
    Date of Patent: December 2, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Detlef Mentzel, Hans-Rudolf Frei