Abstract: The invention concerns a process for the manufacture of collagen membranes for medical applications, in which process the collagen raw materials obtained from cattle or pig collagen are mechanically freed of fatty residues and treated with diluted alkali and acids and, if need be, enzymes. It is thoroughly washed between these steps to thus clean the collagen raw material eliminating the accompanying contamination. It is then processed further while obtaining a collagen matrix with a dry weight of approximately 25% by weight. Thus obtained are collagen membranes, in which the original integral cohesion remains and with which a fast hemostatic effect is achieved; said membranes are also extremely flexible and they adhere well to the surface of a wound.