Patents Represented by Law Firm Pretty, Schroeder, Brueggemann & Clark
  • Patent number: 5756540
    Abstract: In accordance with the present invention, there are provided methods for the in vivo reduction of nitric oxide levels in a mammalian subject. In contrast to the inhibitory approach described in the prior art (i.e., wherein the function of the enzymes responsible for nitric oxide production is inhibited), the present invention employs a scavenging approach whereby overproduced nitric oxide is bound in vivo to a suitable nitric oxide scavenger. The resulting complex renders the nitric oxide harmless, and is eventually excreted in the urine of the host. Further in accordance with the present invention, there are provided compositions and formulations useful for carrying out the above-described methods. An exemplary nitric oxide scavenger contemplated for use in the practice of the present invention is a dithiocarbamate-ferrous iron complex. The present invention relates to methods for reducing in vivo levels of .multidot.NO as a means of treating subjects afflicted with inflammatory and/or infectious disease.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: May 26, 1998
    Assignee: MCW Research Foundation, Inc.
    Inventor: Ching-San Lai
  • Patent number: 5723329
    Abstract: The present invention relates to novel receptor polypeptides, which, upon interaction with certain ligands, or activation by certain compounds, modulate transcription of certain genes by binding to cognate response elements associated with promoters of such genes. The novel receptors of the invention modulate transcription in the presence of retinoid compounds. The receptors of the present invention differ significantly from known retinoic acid receptors, in protein primary sequence and in responsiveness to exposure to various retinoids. The invention provides DNAs encoding the novel receptors, expression vectors for expression of the receptors, cells transformed with such expression vectors, cells co-transformed with such expression vectors and with reporter vectors to monitor modulation of transcription by the receptors, and methods of using such co-transformed cells in screening for compounds which are capable, directly or indirectly, of activating the receptors.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: March 3, 1998
    Assignee: The Salk Institute for Biological Studies
    Inventors: David J. Mangelsdorf, Ronald M. Evans
  • Patent number: 5661384
    Abstract: This disclosure provides a motor control system and method that is preferably applied to cargo power drive units. Power is supplied to a motor having one or more windings and a thermocouple that is embedded in the motor windings. The thermocouple provides an electronic signal from which both motor temperature and rate of temperature change are derived. A motor control circuit uses these values to determine if a jam condition has occurred (as represented by improper temperature rise) or whether critical overheating is occurring. If so, the motor control circuit causes a power switch to disconnect power from one or more PDUs in the subject bank of PDUs. Power is temporarily disabled, until a cargo operator releases a joy stick control to a neutral position and then attempts to use it again.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 26, 1997
    Assignee: Lucas Western, Inc.
    Inventor: Irwin A. Glibbery
  • Patent number: 5659465
    Abstract: An electrical power conversion system that supplies the maximum available output power from a power source such as a solar array to a plurality of loads such as rechargeable batteries. The output power of the solar array peaks at an optimum current that is less than is maximum available output current. The system includes a controller and a plurality of dc-to-dc converters that charge the batteries. The controller monitors the solar array's output power and adjusts the battery charging by generating a current control signal that tracks a peak of the solar array's available output power and sets a current limit such that the combined current draw of the plurality of dc-to-dc converters is substantially equal to the solar array's optimum current at which it provides its maximum available power. The electrical power and control signals are transmitted from the power source and controller to the power converters on three bus bars, including a power bus, a control bus, and a common bus.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: August 19, 1997
    Assignee: Aeroviroment, Inc.
    Inventors: Albert J. Flack, Michael D. Vail
  • Patent number: 5638154
    Abstract: A novel printing plate mounting device and procedure are provided. A small-scale single-color representation of a carton blank or other substrate and a complete usually multi-color image to be printed thereon is projected from an acetate film or other suitable substrate onto a carrier sheet to provide a full-scale single-color representation of the substrate and the image to be printed thereon. A small-scale usually multi-color representation of the carton blank and the complete usually multi-color image to be printed thereon is used as a template to determine which ones of a plurality of individual printing plate elements is used to print which ones of the color of the multi-color image. The individual printing plate elements for each color then are affixed to separate carrier sheets in the position shown by the full-scale single-color representation.
    Type: Grant
    Filed: November 29, 1994
    Date of Patent: June 10, 1997
    Assignee: Napp Systems, Inc.
    Inventor: Reinhold Chmielnik
  • Patent number: 5637800
    Abstract: An ultrasonic transducer array, and a method for manufacturing it, having a plurality of transducer elements aligned along an array axis in an imaging plane. Each transducer element includes a piezoelectric layer and one or more acoustic matching layers. The piezoelectric layer has a concave front surface overlayed by a front electrode and a rear surface overlayed by a rear electrode. The shape of each transducer element is selected such that it is mechanically focused into the imaging plane. A backing support holds the plurality of transducer elements in a predetermined relationship along the array axis such that each element is mechanically focused in the imaging plane.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: June 10, 1997
    Assignee: Parallel Design
    Inventors: P. Michael Finsterwald, Stephen J. Douglas, Ricky G. Just
  • Patent number: 5635235
    Abstract: Masa handling methods for the continuous processing of masa type dough in conjunction with commonly available feed processing equipment, such as a masa extruder, an oven, or cooling apparatus. One masa handling method includes a masa separator having a pair of opposed, endless belt conveyors having facing surfaces spaced apart to receive a generally continuous masa stream output from a nozzle on the masa extruder. When the masa stream moves between the conveyors, it is gripped by their facing surfaces and moved away from the nozzle, causing the masa to be separated into individual pieces, or logs. The masa handling method can also include feeding the masa to masa hoppers fed by at least two endless belt conveyors arranged in upstream and downstream positions relative to each other.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 3, 1997
    Assignee: Machine Masters, Inc.
    Inventors: Victor R. Sanchez, Alberto Ceja, Rigoberto Anguiano
  • Patent number: 5632555
    Abstract: An improved prediction-type medical thermometer that provides an accurate estimate of a patient's temperature in substantially reduced time as compared to prior thermometers of this kind. This improved performance is achieved by using a special hollow probe tip having a low heat capacity and incorporating a resistive heater that is actuated only upon removal of the probe from a base housing. The heater regulates the temperature to a value of about 93.degree. F. After the probe is applied to the patient, a microprocessor repeatedly samples the thermistor and estimates the patient's temperature based on the successive samples. If a predetermined number of successive temperature estimates lie within a predetermined error range, the sampling is terminated and the most recent estimate is displayed as the patient's temperature.
    Type: Grant
    Filed: November 3, 1994
    Date of Patent: May 27, 1997
    Assignee: Diatek, L.P.
    Inventors: Thomas K. Gregory, John W. Stevenson
  • Patent number: 5632142
    Abstract: This disclosure provides a stationary gas turbine power system that develops a reduced back pressure for the gas turbine engine and thus greater efficiency. An enclosed ejector is positioned downstream of the engine's exhaust plane, and means such as a downstream diffuser cause the exhaust stream to entrain air from the ejector enclosure, by natural pumping action, so as to develop a sub-atmospheric pressure within that enclosure and thus at the engine's exhaust plane. This provides substantially improved engine efficiency. The diffuser recovers the static pressure to a level sufficient to drive any downstream devices.
    Type: Grant
    Filed: February 15, 1995
    Date of Patent: May 27, 1997
    Inventor: Robert G. Surette
  • Patent number: 5631129
    Abstract: This invention relates to the use of functional reporter molecules in the detection and measurement of RNA sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of nucleotide sequences, one having a probe sequence linked to a sequence capable of initiating replication by an RNA-dependent RNA polymerase. The other is capable of hybridizing to a strand separated from the extension product of the first nucleotide sequence after hybridization to a specific target sequence. The extension product of the second hybridized nucleotide sequence serves as a template source for autocatalytic replication by the RNA-dependent RNA polymerase. The replication products are detected as a means for detection of nucleic acid sequences.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: May 20, 1997
    Assignee: The Salk Institute for Biological Studies
    Inventors: Barbara C. Chu, Gerald F. Joyce, Leslie E. Orgel
  • Patent number: 5628104
    Abstract: The invention describes a machine tool with a turntable, which has an upper part with a mounting plate which is arranged so as to pivot with respect to a stationary lower part, and is connected to at least one line to deliver fluids or electrical or mechanical energy to the upper part. The lines are brought in from below through the lower part and can be connected by means of coupling means to the upper part, from where they are connected with connection modules that are arranged on the mounting plate. Serration gear is preferably provided to position the upper part on the lower part, so that each pivoting operation is preceded by a lifting operation and ends with a lowering operation. Preferably, lifting and lowering simultaneously open and close, respectively, the coupling modules.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: May 13, 1997
    Assignee: Chiron-Werke GmbH & Co. KG
    Inventors: Eugen R utschle, Hans-Henning Winkler
  • Patent number: 5628092
    Abstract: The invention provides an improved eyewear retainer in which a strap that is attached to the earpieces of the eyewear and looped around the head of a human wearer to retain the eyewear snugly and securely in place on the wearer's head. The strap includes at least one hinge, a region of the strap having increased flexibility in comparison with a region adjacent to the hinge. In preferred embodiments, the hinge is formed by pulling an end of the strap through an aperture through the strap's material. In a particularly preferred embodiment, the strap comprises two strap segments, each of which includes a hinge formed by passing an end of the strap segment through a separate aperture in the material of the strap segment. Each of the strap segments is provided with an attachment for securing the strap segment to an earpiece of the eyewear. The two strap segments are held together by a fastener, which may be formed of a hook and loop material.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: May 13, 1997
    Inventors: Tina Harris, Lisa Quon
  • Patent number: 5629595
    Abstract: An apparatus and method in which a vehicle is guided along a path defined by a centerline and left and right boundaries parallel to and spaced laterally on opposite sides thereof and in which a passenger in the vehicle can steer it for lateral movement between the boundaries. The method and apparatus utilize an electrical conductor to define the center of the pathway and a sensor for sensing the position of the vehicle relative to the electrical conductor. Based on a comparison of the position of the vehicle and the steering command received from the passenger, as well as the steer angle position of the vehicle, the vehicle is confined to a predetermined envelope, while permitting the passenger to steer the vehicle within the envelope.
    Type: Grant
    Filed: June 19, 1995
    Date of Patent: May 13, 1997
    Assignee: The Walt Disney Company
    Inventors: Kenneth D. Salter, Daniel A. Armstrong, John D. Charlesworth, Robert S. Bollinger
  • Patent number: 5627338
    Abstract: A system and method for launching projectiles, such as fireworks projectiles, which explode in the air into a pyrotechnic display. The projectile includes a shell constructed from a binding agent and an explosive additive which explodes the shell into small particles. The explosive additive, which may be nitrocellulose, causes the exploded particles to be rapidly burned and consumed to form lightweight, inert flakes that fall harmlessly to the ground. The projectile is aimed and launched by a launcher to rapidly expel the projectile from a launching tube. Once in the air at a predetermined location in the sky, a fuse inside the projectile operates to detonate the projectile into its intended pyrotechnic display. The fuse is extremely accurate and enables detonation of the projectile at precise altitudes. An electronic control system controls launching and detonation of the projectiles in a precise and repeatable manner.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 6, 1997
    Assignee: The Walt Disney Company
    Inventors: Kyle W. Poor, B. Thomas Craven, Bernard M. Durgin
  • Patent number: 5624365
    Abstract: A machine tool (10) has a revolving spindle (14) borne in a spindle tube (13) which has a locating opening (15) to receive tool holders; (16, 17). A tool magazine (55) is also provided to hold a number of tool holders. Moreover, a tool changer (18) with at least two gripper arms (21, 22) is provided to transport tool holders; (16, 17) between a transfer position (23) in the area of the tool magazine (55) and a common spindle position (24) beneath the locating opening (15). A holding device (31) bearing the tool changer (18) is borne on the spindle tube (13) in such a way that it can be moved longitudinally in the sense of a stroke movement (33) and transfer the respective tool holder (16) from the spindle position (24) into its working position in the locating opening (15). The holding device (31) is borne on the spindle tube (13) along its longitudinal axis so that it can be rotated in such a way that the gripper arms (21, 22) have a common transfer position (23) to the tool magazine (55).
    Type: Grant
    Filed: June 13, 1995
    Date of Patent: April 29, 1997
    Assignee: Chiron-Werke GmbH & Co. KG
    Inventors: Rudolf Haninger, Hans-Henning Winkler
  • Patent number: 5623878
    Abstract: A dynamic ride vehicle for executing a sequence of distinct motion patterns and for providing unique ride experiences in an amusement park attraction or other environment includes a movable chassis and a body having a passenger seating area. A motion apparatus, including computer controlled actuators, imparts motion to the body along a plurality of axes independent of any motion of the chassis as it moves along a path. As the vehicle travels along the path, articulation of the body and appropriate steering of the vehicle enables the vehicle to execute, in cooperation with the motion apparatus, a sequence of distinct motion patterns. Execution of the motion patterns enhances the passengers' sensation of vehicle movement that is actually taking place, as well as the sensation of a realistic moving ride vehicle experience that is actually not happening.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: April 29, 1997
    Assignee: The Walt Disney Company
    Inventors: Anthony W. Baxter, David G. Fink, William G. Redmann, Jon H. Snoddy, David W. Spencer, II, Scott F. Watson
  • Patent number: D379263
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: May 20, 1997
    Assignee: Jobar International, Inc.
    Inventor: Mitchell F. Sussman
  • Patent number: D379693
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: June 3, 1997
    Assignee: Letro Products, Inc.
    Inventors: Sanford F. Campbell, Robert E. Jones
  • Patent number: D379817
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: June 10, 1997
    Assignee: Califone International, Inc.
    Inventor: Teng K. Lin
  • Patent number: D381189
    Type: Grant
    Filed: July 27, 1995
    Date of Patent: July 22, 1997
    Assignee: R.S.V. Sport, Inc.
    Inventor: Mel B. Geliebter