Abstract: A system and method enables the creation of medical images using data related to ghost artifacts. The method thus allows components of an imaged subject to be segmented based on state changes in the components that lead to the controlled production of ghost artifacts. This is achieved in MR by performed a pulse sequence so that multiple sets of MR data are acquired in which the signals from a target tissue vary across the data sets while the signals from a background tissue do not vary across the data sets. A composite data set is generated by populating selected k-space lines of the composite data set with information from a first MR data set and populating the remaining k-space lines of the composite data set with information from a second MR data set. An MR image is then reconstructed from the composite data set.

Abstract: An MRI system produces a three-dimensional image by acquiring NMR signals that fully sample a central region of k-space and partially sample peripheral region of k-space. Specifically, k-space is arranged as a three-dimensional (3D) Cartesian grid of points that is divided into a central region of k-space and a peripheral region of k-space. Points are selected in k-space within a plurality of radial vanes that extend radially outward from the central region of k-space through the peripheral region of k-space as viewed in a plane sampled by two phase encoding gradients to create a plurality of gaps between the radial vanes that is substantially a factor of N times greater in area than the radial vanes. Using an MRI system having arrays of RF receiver coils, NMR signals are acquired from a subject to fully sample the central region of the 3D k-space and undersample the peripheral region of k-space by only sampling k-space within the plurality of radial vanes.

Abstract: An integrin antagonist reduces the occurrence of cross-linked actin network (CLAN) structures in cells of the trabecular meshwork. CLAN structures are associated with steroid-induced glaucoma. Reduction in CLAN structures is associated with increased aqueous humor outflow facility from the trabecular meshwork.

Abstract: A modular conveying assembly for reducing backline pressure when accumulating products includes a first roller belt module having a top surface and at least one first roller axle support extending above the top surface. The first axle support includes an opening. A second roller belt module adjacent to the first roller belt module has a top surface and at least one second roller axle support extending above the top surface. The second axle support includes an opening coaxial with the opening formed in the first roller axle support. A roller axle extends through the openings of the first and second axle supports. At least one roller is rotatably supported by the roller axle to reduce friction between the roller belt modules and an object carried along the conveyer belt assembly.

Abstract: A method of antigen-capture assays that uses the detection of antigens secreted into liquid culture is provided. Also provided are antibodies to Mycobacterium avium complex-specific antigens, and diagnostic kits and systems for the detection of the presence of mycobacteria in liquid samples.

Abstract: An apparatus and method are disclosed to configure, format, and test, a data storage subsystem product. The method supplies a data storage subsystem product comprising one or more host computer ports, a processor, one or more data storage device ports, and one or more data storage devices interconnected to the one or more data storage device ports. The method further supplies a configuration appliance comprising a storage configuration. The method connects the configuration appliance to one of the one or more storage device ports, boots up the data storage subsystem product, discovers the configuration appliance by the data storage subsystem product, imports storage configuration data into the data storage subsystem product, formats the one or more data storage device, and tests the input and output data transfer rates for the data storage subsystem product, wherein the formatting and testing are initiated concurrently.

Abstract: The present invention provides counter flow cascade separation systems useful to separate solute/solute pairs present in a solvent. The separation systems include a series of interconnected stages with each stage comprising a diafilter preferentially permeable for one solute. Solute/solute pairs are preferentially separated by the diafilter into permeate and retentate flows. Stages are combined to form separation systems capable of operation approaching an ideal cascade.

Abstract: A method of differentiating embryonic stem cells into ventral spinal progenitor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority of cells that are characterized by an early rosette morphology and are Sox1?/Pax6+ in the presence of retinoic acid, wherein the cells express Hoxb4, but not Otx2 or Bf1.

Abstract: The present invention relates to ambulance cots, cot systems and methods of using the same. In particular, the present invention provides an ambulance cot comprising a hydraulic system and a tip angle monitoring, recording and alert system, and methods of using the same (e.g., to transport subjects and/or to detect and/or record operational data related to cot usage).

Abstract: A system and method is provided for simultaneously designing a radiofrequency (“RF”) pulse waveform and a magnetic field gradient waveform in a magnetic resonance imaging (“MRI”) system. The method includes determining a desired pattern of RF excitation and determining, from the desired pattern of RF excitation, a plurality of k-space locations indicative of the magnetic field gradient waveform and a plurality of complex weighting factors indicative of RF energy deposited at each k-space location. The method also includes calculating, from the determined k-space locations, the magnetic field gradient waveform and calculating, from the complex weighting factors, the RF pulse waveform that will produce the desired pattern of RF excitation when produced with the calculated magnetic field gradient.

Abstract: A method and apparatus for converting three phase AC voltages on first, second and third input lines to DC voltage across positive and negative DC buses, the apparatus comprising a rectifier including first, second and third rectifier legs, each leg including a switch and a diode wherein the switch is linked between the positive DC bus and an cathode of the diode, an anode of the diode is linked to the negative DC rail and the first, second and third diode cathodes are linked to the first, second and third input lines, respectively, a DC bus voltage sensor linked to the positive DC bus and measuring the DC bus voltage to generate a measured DC bus voltage and a rectifier controller that receives the measured DC bus voltage, a reference voltage value and the three phase AC voltages wherein, when the measured DC bus voltage is at least equal to the reference voltage value, the controller turns on the switches in the first, second and third rectifier legs when the voltages on the first, second and third input li

Abstract: A method for magnitude constrained phase contrast magnetic resonance imaging (MRI) is provided. The method utilizes an assumption that the image magnitude is shared across a series of images reconstructed from a set of phase contrast enhanced k-space data. In this manner, one common magnitude image and a plurality of phase images are reconstructed substantially contemporaneously from the acquired image data. The method is further applicable to other phase contrast MRI methods, such as phase contract velocimetry. Moreover, simultaneous phase contrast velocimetry and chemical shift imaging, in which water and fat signal separation is achieved, is provided.

Abstract: A multi-door enclosure includes an enclosure body, a primary door having an actuator and a secondary door. An interlock member having a holding section extends between the primary door and the secondary door. As the primary door closes, the actuator contacts the interlock member to translate the interlock member towards the secondary door until the holding section engages the secondary door.

Abstract: A method for reducing maximum local specific absorption rate (“SAR”) in a magnetic resonance imaging (“MRI”) system is disclosed. More specifically, a plurality of candidate radio frequency (“RF”) pulses are designed and the manner in which they are applied to a subject is determined such that the maximum local SAR is substantially reduced relative to applying the candidate RF pulse that produces the lowest maximum local SAR alone. Put another way, this “time-multiplexing” of a set of RF pulses that each produce approximately the same excitation pattern yields a lower maximum local SAR than does transmitting the individual RF pulse having the lowest local SAR over many repetition times (“TRs”). A convex optimization method is utilized to determine the manner in which the RF pulses are multiplexed in time such that a substantially lower maximum local SAR is achieved.

Abstract: A control system for a slide-out room of a recreational vehicle includes a number of room slides which move the slide-out room between retracted and extended positions. If multiple room slides are used, a controller synchronizes the movement of the room slides to prevent damage to the components of the system. The retracted and extended positions of the slide-out room can be reset by the end user. The controller is also capable of detecting faults and communicating faults to the user via LEDs on a control panel. The controller automatically stops the motion of the slide-out room if a fault is detected. The control system includes a lock which is automatically disengaged before motion of the slide-out room. The lock is also automatically engaged when the slide-out room moves to the retracted position.

Abstract: A piston for a control valve of a water treatment apparatus includes a body having a central portion from which at least one flange projects radially outward. Each flange has an outer peripheral surface extending around the central portion with an annular groove therein. The annular groove is undercut thereby having a width that increases from the peripheral surface radially inward into the flange. A separate sealing ring is molded into the groove of each flange and is captivated therein by the undercut of the groove. That captivation better enables each sealing ring to resist forces produced by the water flowing through the control valve without becoming dislodged from the flange.

Abstract: A power supply module removably disposed within an automated data storage and retrieval system. An automated data storage and retrieval system which includes one or more power supply modules removably disposed therein. An accessor movably disposed with an automated data storage and retrieval system comprising a gripper mechanism which can be releasably attached to a power supply module. A method to supply power to an automated data storage and retrieval system. A method to monitor the operation of a power supply module removably disposed within an automated data storage and retrieval system.

Abstract: A device for performing an anterior capsulotomy procedure and a method using the same is presented. The device includes a body having a rotatable cutting element rotatably disposed on the proximal end. The cutting element further includes multiple surgical blades. In certain embodiments, the device further includes an arcuate member, wherein two surgical blades are attached at opposing ends and extend outwardly from the arcuate member. In using the device to perform an anterior capsulotomy, the device is inserted into an incision made in an eye and the surgical blades are brought in contact with the anterior capsule wall. The anterior capsule wall is then transformed by rotating the rotatable cutting element, creating an aperture there through.

Abstract: Methods of increasing the thickness of the epidermal layer in the skin of a human comprising topically administering a therapeutically effective dose of an active pharmaceutical ingredient comprising a vitamin D analog including 2-methylene-19-nor-20(S)-1?-hydroxy-bishomopregnacalciferol, 19-nor-26,27-dimethylene-20(S)-2-methylene-1?,25-dihydroxyvitamin D3, 2-methylene-19-nor-(24R)-1?,25-dihydroxyvitamin D2, 2-methylene-1?,25-dihydroxy-(17E)-17(20)-dehydro-19-nor-vitamin D3, 2-methylene-(20R,25S)-19,26-dinor-1?,25-dihydroxyvitamin D3, 2-methylene-18,19-dinor-(20S)-1?,25-dihydroxyvitamin D3, 2-methylene-19-nor-1?-hydroxy-pregnacalciferol, 1?-hydroxy-2-methylene-19-nor-homopregnacalciferol, (20R)-1?-hydroxy-2-methylene-19-nor-bishomopregnacalciferol, 2-methylene-(20S)-19-nor-1?-hydroxy-trishomopregnacalciferol, 2-methylene-(20R)-23,23-difluoro-1?-hydroxy-19-nor-bishomopregnacalciferol, 2-methylene-(20S)-23,23-difluoro-1?-hydroxy-19-nor-bishomopregnacalciferol, 2-(3?hydroxypropyl-1?,2?-idene)-19,23,24-trinor-(20

Abstract: Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten the polymeric molecules and attach the straightened molecules to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge.