Patents Represented by Attorney Quine I. P. Law Group, PC.

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  • Heregulin variants
    Patent number: 7063961
    Abstract: The present invention provides heregulin variants that are capable of binding an ErbB receptor. Included in the invention are variants of human heregulins, and, in particular, variants of human heregulin-?1 having enhanced affinity for the ErbB-3 and ErbB-4 receptors. These variants include at least one amino acid substitution and can include further modifications. The invention also provides nucleic acid molecules encoding heregulin variants and related vectors, host cells, pharmaceutical compositions, and methods.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: June 20, 2006
    Assignee: Genentech, Inc.
    Inventors: Marcus D. Ballinger, Jennifer T. Jones, Wayne J. Fairbrother, Mark X. Sliwkowski, James A. Wells
  • Light controlled gene expression utilizing heterologous phytochromes
    Patent number: 6887688
    Abstract: This invention relates to the field of gene expression. In particular this invention relates to the use of heterologous phytochromes to translocate polypeptides into the nucleus of a cell. Where the polypeptides comprise transactivators or repressors this invention provides a system for light-directed gene expression.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: May 3, 2005
    Assignee: The Regents of the University of California
    Inventors: John Clark Lagarias, Takayuki Kochi, Nicole Frankenberg, Gregory A. Gambetta, Beronda L. Montgomery