Patents Represented by Attorney R. Cole Harrington

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  • Non-steroidal ligands for the estrogen receptor
    Patent number: 5877219
    Abstract: Described herein are non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: March 2, 1999
    Assignee: Glaxo WellcomeInc.
    Inventor: Timothy Mark Willson
  • Anesthetic use of N-phenyl-N-(4-piperidinyl)amides
    Patent number: 5466700
    Abstract: The use of particular opioids to induce and maintain anesthesia and conscious sedation is disclosed. The opioids used in the method of the present invention relate to the anesthetic action of the N-phenyl-N-(4-piperidinyl)amides as disclosed in U.S. Pat. No. 5,019,583 to Feldman, et al.
    Type: Grant
    Filed: August 30, 1993
    Date of Patent: November 14, 1995
    Assignee: Glaxo Wellcome Inc.
    Inventors: Randal L. Batenhorst, Anthony W. Fox
  • Intermediates for making analgesic N-phenyl-N-(3-OR.sup.1 -3-Me-4-piperidinyl)amides
    Patent number: 5387688
    Abstract: Novel piperidinyl intermediates as set forth below wherein R, R.sup.1 and Ar are as set forth in the specification and W is either hydrogen or benzyloxycarbonyl. The intermediates are useful in the preparation of N-phenyl-N-(4-piperidinyl) amides having potent analgesic activity.
    Type: Grant
    Filed: December 11, 1992
    Date of Patent: February 7, 1995
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Modulators of cholecystokinin
    Patent number: 5380872
    Abstract: CCK modulators, e.g. agonists or antagonists, of the following formula (I): ##STR1## or a base-addtion salt thereof.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: January 10, 1995
    Assignee: Glaxo Inc.
    Inventors: Elizabeth E. Sugg, Milana Dezube, Gavin C. Hirst