Abstract: The present invention features nucleic acids and polypeptides encoding novel splice variant isoforms of acetyl-CoA carboxylase 2 (ACC2). The polynucleotide sequence of ACC2sv1 is provided by SEQ ID NO 3. The amino acid sequence of ACC2sv1 is provided by SEQ ID NO 4. The present invention also provides methods for using ACC2sv1 polynucleotides and proteins to screen for compounds that bind to ACC2sv1.
Type:
Grant
Filed:
June 3, 2005
Date of Patent:
December 19, 2006
Assignee:
Rosetta Inpharmatics LLC
Inventors:
Zhengyan Kan, Philip W. Garrett-Engele, Christopher D. Armour, Christopher K. Raymond, John C. Castle