Abstract: Disclosed is a class of pyrrolo?2,3-b!pyridine derivatives of formula (I) wherein Q represents a moiety of formula Qa or Qb, which are ligands for dopamine receptor subtypes within the body, in particular the dopamine D4 receptor subtype and are therefore useful in the treatment and/or prevention of disorders of the dopamine system, including schizophrenia.

Abstract: The compounds of formula (I) ##STR1## wherein R is selected from the group hydroxymethyl and carboxy, have been identified as metabolites of 5.alpha.-23-methyl-4-aza-21-nor-chol-1-ene-3,20-dione and are believed to be active as testosterone 5.alpha.-reductase inhibitors and would thus be useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.

Abstract: Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group include heteroorganic radicals containing silane, silicone, ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups.These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce mostly aldehydes derived from terminal attack on the alpha-olefin reactant.

Abstract: Branched alkyl diaryl phosphine rhodium carbonyl hydride complexes are surprisingly effective, stable and selective hydroformylation catalysts particularly in the presence of a large excess of t-phosphine ligands. As such, they are advantageously employed as catalysts in a novel low pressure rhodium hydroformylation process producing normal and iso aldehydes by reacting olefins with H.sub.2 and CO.

Abstract: 3-Phosphonate carbapenems of the Formula: wherein R.sup.1 is hydrogen, alkyl, amino, --NHCO-alkyl, hydroxy, alkoxy, halo, hydroxyalkyl, carboxyl or trifluoromethyl; R.sup.2 is alkyl, substituted alkyl, heterocyclic or substituted heterocyclic; R.sup.3 is hydrogen, alkyl or substituted alkyl; and M is a metal cation of H.sup.+ are disclosed. The compounds are useful as antibiotics.

Abstract: Iron-cobalt spinels which contain low levels of cobalt, in an iron/cobalt atomic ratio of 7:1 to 35:1, are converted to Fischer-Tropsch catalysts upon reduction and carbiding that exhibit high activity and selectivity to C.sub.2 --C.sub.6 olefins and low CH.sub.4 production.

Abstract: The use of relatively stable iron carbonyl complexes e.g. Bis(dicarbonylcyclopentadienyliron), and lower melting cobalt carbonyl complexes, facilitates production of mixed metal catalysts for conversion of CO/H.sub.2 to alpha-olefins. The decomposition of these materials can be achieved in a controlled manner resulting in an excellent alpha-olefins synthesis catalyst in Fischer-Tropsch processes.