Patents Represented by Attorney, Agent or Law Firm Rachel Polster
  • Gem-substituted &agr;v&bgr;3 antagonists
    Patent number: 6531494
    Abstract: The present invention relates to a class of compounds represented by the Formula I. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the &agr;V&bgr;3 and/or the &agr;V&bgr;5 integrin.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: March 11, 2003
    Assignee: Pharmacia Corporation
    Inventors: Ish Kumar Khanna, Yi Yu, Balekudru Devadas, Hwang-Fun Lu, Nizal S Chandrakumar, Renee M. Huff, Bipinchandra N. Desai, Srinivasan Raj Nagarajan, Alan F. Gasiecki, Thomas D. Penning, Mark A. Russell, Mark L. Boys, Lori A. Schretzman, Barbara B. Chen, Thomas Rogers, John Adam Wendt, Albert Khilevich, Yaping Wang
  • &agr;&ngr;&bgr;3 integrin antagonists in combination with chemotherapeutic agents
    Patent number: 6372719
    Abstract: The present invention is directed to compounds of the formula and pharmaceutically acceptable salts and isomers thereof administered in combination with chemotherapeutic agents.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: April 16, 2002
    Inventors: Jay Cunningham, Gary B. Gordon, G. Allen Nickols, William F. Westlin, Thomas Edward Rogers, Peter Gerrard Ruminski