Patents Represented by Attorney, Agent or Law Firm Ralph Palo
  • Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders
    Patent number: 6380224
    Abstract: Amine and amide derivatives of the formula: which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing amines and amides of formula A as the active ingredient are described. The amines and amides of formula A are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: April 30, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Scott L. Dax, James McNally, Mark Youngman
  • Anticonvulsant derivatives useful in treating obesity
    Patent number: 6071537
    Abstract: A method for treating obesity comprising administering a therapeutically effective amount of a compound of the formula: ##STR1## is disclosed.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: June 6, 2000
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Richard P. Shank
  • Azole peptidomimetics as thrombin receptor antagonists
    Patent number: 6017890
    Abstract: Azole derivatives of formula (I): ##STR1## are disclosed as useful in treating platelet-mediated thrombotic disorders.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: January 25, 2000
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: William Hoekstra, Becky L. Hulshizer
  • Arylmethylphosphonic acid derivatives useful in treating bone wasting diseases
    Patent number: 5994563
    Abstract: Benzyl-phosphonate compounds represented by the formula I: ##STR1## are disclosed as useful in treating bone wasting diseases and as an immunosuppresant.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: November 30, 1999
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Scott Beers, Roger F. Frechette, Elizabeth A. Malloy, Charles Schwender, Wei Wu