Patents Represented by Attorney Randolph Bretton

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  • Protein C variant
    Patent number: 7785857
    Abstract: This invention relates to a novel form of protein C or activated protein C. More specifically, the invention is directed to a variant of protein C that is activated at a higher rate than wild-type or other variants and produces an activated protein C with reduced anticoagulant properties while retaining the protective anti-inflammatory and anti-apoptotic properties of wild-type activated protein C. This novel APC variant will be beneficial for treating inflammatory and apoptotic disorders with a reduced risk for bleeding.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: August 31, 2010
    Assignee: Saint Louis University
    Inventors: Alireza R. Rezaie, Likui Yang