Abstract: A device for the unidirectional transdermal administration of a drug in an ointment, cream or jelly-like carrier comprising a laminar applicator adapted to receive a predetermined quantity of the drug on a skin-contacting surface thereof, the applicator including a drug-impervious lamina such as a layer of aluminum foil, overlying said skin-contacting surface, such that in use a unidirectional transfer of the drug from the carrier to the skin surface is ensured. The device is especially suitable for the transdermal administration of nitroglycerin, clonidine, methadone and scopolamine or any drug that is skin-permeable. The drug receiving surface may be embossed, pressed, or stamped to define one or more mini-recesses or receptacles for receiving the drug to be administered.