Abstract: Methods and compositions for the prevention and/or treatment of cardiovascular diseases, the methods comprising administering to individuals in need thereof, an effective amount of a non-steroidal anti-inflammatory drug alone or in combination with other conventional therapies to induce apoptosis, reduce proliferation, induce quiescence, inhibit cell migration, or influence cell differentiation of the cells in the vascular wall and or/induce hypolipidemia.
Type:
Grant
Filed:
December 8, 1998
Date of Patent:
March 13, 2001
Assignees:
The Rockefeller University, Mt. Sinai School of Medicine, Columbia University
Inventors:
Steven Shiff, Edward A. Fisher, I. Bernard Weinstein, Hayes M. Dansky, Urnani Reiss