Patents Represented by Attorney Ray M. Speer

Find this attorney in the Justia Lawyer Directory

  • Cysteine-modified acidic fibroblast growth factor
    Patent number: 5223483
    Abstract: Mutant human acidic fibroblast growth factor proteins are recombinantly produced having replaced cysteine residues with amino acids incapable of disulfide bond formation. The recombinantly produced mutant human acidic fibroblast growth factor proteins have improved biological activity in the absence of heparin when compared to wild-type recombinant human acidic fibroblast growth factor.
    Type: Grant
    Filed: August 28, 1992
    Date of Patent: June 29, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Thomas, David L. Linemeyer