Patents Represented by Attorney Rececca M. Hale

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  • Method for producing yeast expressed HPV types 6 and 16 capsid proteins
    Patent number: 7112330
    Abstract: Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production conformational antibodies against both L1 proteins upon administration to mice.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: September 26, 2006
    Assignee: Chiron Corporation
    Inventors: Daniela Tornese Buonamassa, Catherine E. Greer, Cesira L. Galeotti, Giuliano Bensi, Roberto Petracca