Abstract: Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
Type:
Grant
Filed:
October 14, 2009
Date of Patent:
January 8, 2013
Assignee:
The University of Tennesee Research Foundation
Inventors:
Bob M. Moore, II, Steven Gurley, Suni Mustafa
Abstract: Unconventional twisted ?-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state.
Abstract: The invention relates to novel ligands of the estrogen receptors ? and ? of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for the treatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention.
Type:
Grant
Filed:
May 5, 2009
Date of Patent:
December 18, 2012
Assignees:
Ustav Molekularni Genetikv AV CR, V.V.I., Ustav Organicke Chemie A Biochemie AV CR, V.V.I., Univerzita Karlova V Praze, Prirodovedecka Fukulta UK
Inventors:
Petr Novak, David Sedlak, Petr Bartunek, Martin Kotora
Abstract: An improved apparatus and method are provided, for pumping fluids, such as water and/or hydrocarbons, from a subterranean formation or reservoir, through use of a cranked rod pumping (CRP) apparatus for imparting reciprocating substantially vertical motion to a rod of a sucker-rod pump having a pump stroke. The CRP apparatus includes a motor driven cranked mechanical actuator arrangement. The cranked mechanical actuator arrangement includes a substantially vertically moveable member attached to the rod of the sucker-rod pump for imparting and controlling vertical motion of the rod of the sucker-rod pump. The actuator arrangement may include pneumatic counterbalancing.
Type:
Grant
Filed:
October 15, 2008
Date of Patent:
December 11, 2012
Assignee:
Unico, Inc.
Inventors:
Thomas L. Beck, Ronald G. Peterson, Michael A. MacDonald, Michael D. Dry
Abstract: An extendable mobile fluid carrying apparatus including a first frame configured to couple to a tractor. A fluid container is coupled to the first frame and configured to rotate about a pivot device of the first frame. The container defines a closable orifice configured to decant a fluid from the container. A high-CFM blower is coupled to the container and configured to draw a vacuum. A lift mechanism is coupled to the first frame and the fluid container and configured to lift the fluid container to an angle greater than 45° relative to the first frame. A second frame is slidingly coupled to the first frame, with the second frame configured to extend away from the first frame a predetermined distance. The second frame includes a wheel set. The tractor may include a power takeoff mechanism coupled to a prime mover and to the blower.
Type:
Grant
Filed:
August 5, 2010
Date of Patent:
December 11, 2012
Assignee:
Advanced Waste Services, Inc.
Inventors:
Michael T. Malatesta, Jeff R. Dean, Patrick G. Wheaton, Jason P. Derby
Abstract: Various methods related to the preparation of transparent electrical conductors based on carbon nanotubes having enhanced optical and electrical properties are disclosed. In some embodiments, the methods involve employing carbon nanotubes that have been presorted according to electronic type and/or optical absorbance for use in transparent electrical conductors. Other embodiments involve use of carbon nanotube bundles that have been pre-sorted according to bundle density.
Abstract: Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z are as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors, such as, for example, inflammation.
Type:
Grant
Filed:
September 19, 2011
Date of Patent:
December 4, 2012
Assignee:
University of Tennessee Research Foundation
Inventors:
Bob M. Moore, II, Steven Gurley, Suni Mustafa, Patrick Allison
Abstract: A dental prosthesis removal tool includes a handle portion and a top portion, the top portion including a head portion and a beak portion. The beak portion is configured to engage both a maxillary dental prosthesis and a mandibular dental prosthesis without the tool needing to be reoriented. The dental prosthesis removal tool makes it possible for a dental prosthesis wearer to remove dental prostheses without the user placing his or her fingers inside of his or her mouth. The dental prosthesis removal tool also allows a denture wearer to remove dental prostheses without bending, work hardening, or breaking metal clasps contained in some dental prostheses. The dental prosthesis removal tool further allows a denture wearer to more comfortably remove his or her dental prosthesis, promoting better patient compliance with maintenance procedures and oral hygiene.
Abstract: Polymer-graphite compositions and related methods of using solid-state shear pulverization as can be used to affect one or more physical properties thereof.
Type:
Grant
Filed:
February 25, 2011
Date of Patent:
November 6, 2012
Assignee:
Northwestern University
Inventors:
John M. Torkelson, Katsuyuki Wakabayashi
Abstract: A field asymmetric ion mobility spectrometer (FAIMS) has an analyte ion source assembly by which an analyte substance is ionized and supplied to the inlet of the spectrometer. The ion source assembly has an upstream source of clean, dry air and two ion sources of opposite polarity arranged at the same distance along the flow path. The ion sources are arranged so that the overall charge of the plasma produced is substantially neutral. The analyte substance is admitted via an inlet downstream of the ion sources and flows into a reaction region of enlarged cross section to slow the flow and increase the time for which the analyte molecules are exposed to the plasma.
Type:
Grant
Filed:
April 1, 2008
Date of Patent:
October 30, 2012
Assignee:
Smiths Detection-Watford Limited
Inventors:
Alastair Clark, Stephen John Taylor, Robert Brian Turner, Richard Turner, legal representative, William Angus Munro
Abstract: A method of manufacturing paint roller covers is disclosed in which the paint roller covers are manufactured from a seamless, tubular fabric sleeve knitted in a pile side-in manner and including at least one of a backing material and a pile made, at least in part, from a low melt fiber or yarn component. The seamless, tubular fabric sleeve is inverted to a pile side-out configuration, placed onto a cylindrical member, and heat is applied to cause the low melt fiber or yarn in the backing and/or looped ends of the pile to be activated and to closely conform to the size of the cylindrical member, thereby causing the melted and fused together, re-hardened low melt component of the seamless, tubular fabric sleeve to remain in a cylindrical configuration, forming an integrally formed core member.
Abstract: Compounds and related compositions and methods as can be used to inhibit neuronal nitric oxide synthase and can be employed in the treatment of various neurodegenerative diseases, such compounds of a formula
Abstract: An ion mobility spectrometer has an inlet for an analyte substance opening into an ionization region that produces ions of the substance. Parallel grid electrodes extend laterally across the ion flow path and apply an electric field to the ions that is switchable between a relatively low magnitude alternating field that varies in magnitude over multiple periods and an asymmetric alternating field of sufficiently high magnitude to cause differential mobility effects. A collector collects the passed ions, and an indication of the nature of the analyte substance is produced from the collected ions passed during both the low and high field intervals. Also disclosed is the application of a substantially alternating field between the electrodes, which field varies between a low value and a higher value over a time exceeding that of the alternating period.
Type:
Grant
Filed:
April 25, 2008
Date of Patent:
October 30, 2012
Assignee:
Smiths Detection-Watford Limited
Inventors:
Robert Brian Turner, Richard Turner, legal representative
Abstract: A method and system that provides a unique data display tool for use in the investment area and utilizes color coated entries in various data displays to aid in the client's assimilation of investment data and information. More specifically, the method and system uses a plurality of colors that are superimposed over data contained in various data category displays. Any one category data may contain a number of different such colored overlays. It is between different data displays, the same color would be used for the same data category presented in each display.
Type:
Grant
Filed:
June 7, 2011
Date of Patent:
October 16, 2012
Assignee:
Spectrum Investment Advisors, Inc.
Inventors:
James F. Marshall, Jonathan J. Marshall
Abstract: An automated drug dispensing system includes a cabinet adapted to store a variety of prepackaged pharmaceuticals in a plurality of bins for filling patient prescriptions. Each bin stores a particular variety of packaged multiple-dose pharmaceutical. Each variety of pharmaceutical is associated with a particular code. A controller receives request signals and in response generates dispense signals. Each bin includes a dispenser coupled to the controller for dispensing the packaged pharmaceuticals therefrom in response to a dispense signal sent from the controller. After a package is dispensed, a code reader determines the code of the dispensed package and verifies whether the code on the dispensed package matches the code of the requested package.
Type:
Grant
Filed:
June 20, 2011
Date of Patent:
October 2, 2012
Assignee:
Telepharmacy Solutions, Inc.
Inventors:
Harold J. Liff, Brian T. Hart, Robert L. Wallace, Arthur A. Berube, Richard D. Hart, Enea W. Bossi
Abstract: A system for cutting blocks of food product into bars of substantially equal weight. The system includes a cutter conveyor configured to receive incoming blocks of food product and move the blocks along an in-line processing path in a plane for cutting; a programmable logic controller coupled to the cutter conveyor; and, multiple stations associated with the cutter conveyor. One such station is a camera vision system configured to create an image of the slab portion, and further including a camera controller coupled to the vision system and the PLC, and configured to determine an optimized cut solution of the slab portion from the image and data related to the food product, and is configured to provide the cut solution to the PLC. The PLC is configured to control the cutting of the food product, based on the optimized cut solution, into bars of substantially equal weight.
Abstract: A system and method that provides an enhancement to an overdraft protection program at a financial institution. The debt protection of the program is funded by the financial institution rather than by a consumer/user of the financial account at the financial institution. Under the debt protection program, if the consumer dies, becomes disabled, or becomes involuntarily unemployed and such facts are established to a reasonable degree, the debt protection program will automatically repay the overdraft in full including cost and fees up to a predetermined maximum amount. The payment can occur in a single payment or over a period of time, for example monthly, until the predetermined maximum amount is reached.