Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted IGFBP-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted IGFBP-like polypeptides, compositions, and methods of use for such polypeptides including in cancer.
Type:
Grant
Filed:
August 12, 2002
Date of Patent:
September 19, 2006
Assignee:
Nuvelo, Inc.
Inventors:
Douglas A. Dedera, Victoria Yamazaki, Vinod Asundi, Chenghua Liu, Y. Tom Tang, Radoje T. Drmanac