Patents Represented by Attorney, Agent or Law Firm Renee M. Kosslak, Esq.
  • Protein and peptide sensors using electrical detection methods
    Patent number: 6824669
    Abstract: The present invention provides an apparatus and methods for the electrical detection of molecular interactions between a probe molecule and a protein or peptide target molecule, but without requiring the use of electrochemical or other reporters to obtain measurable signals. The methods can be used for electrical detection of molecular interactions between probe molecules bound to defined regions of an array and protein or peptide target molecules which are permitted to interact with the probe molecules.
    Type: Grant
    Filed: February 17, 2000
    Date of Patent: November 30, 2004
    Assignee: Motorola, Inc.
    Inventors: Changming Li, Jaymie Robin Sawyer, Vi-En Choong, George Maracas, Peiming Zhang
  • Apparatus and method for automated protein design
    Patent number: 6804611
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: October 12, 2004
    Assignee: California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. Benjamin Gordon, Arthur Street
  • Apparatus and method for automated protein design
    Patent number: 6801861
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: October 5, 2004
    Assignee: California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. Benjamin Gordon, Arthur Street, Yaoying Su
  • Apparatus and method for automated protein design
    Patent number: 6792356
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: September 14, 2004
    Assignee: California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. Benjamin Gordon, Arthur Street
  • Magnetic resonance imaging agents for the detection of physiological agents
    Patent number: 6770261
    Abstract: The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: August 3, 2004
    Assignee: Research Corporation Technologies
    Inventors: Thomas J. Meade, Scott Fraser
  • Printed circuit boards with monolayers and capture ligands
    Patent number: 6761816
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: July 13, 2004
    Assignee: Clinical Micro Systems, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Target analyte detection using asymmetrical self-assembled monolayers
    Patent number: 6753143
    Abstract: The present invention relates to the use asymmetric monolayer forming species and electroconduit forming species to detect target analytes.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: June 22, 2004
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Chunlin Tao, Changjun Yu
  • Method for increasing the permeability of wood
    Patent number: 6742278
    Abstract: The present invention relates to the treatment of wood, and is particularly concerned with a method for increasing the permeability of wood, especially moist wood.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: June 1, 2004
    Assignee: The University Of Melbourne
    Inventors: Peter Vinden, Francisco Javier Romero, Grigory Torgovnikov