Patents Represented by Attorney Reusse Brownlee Wolter Mora & Maire
  • Patent number: 6943145
    Abstract: The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridine pyridinium salt-type redox targetor moiety, a bulky lipophilic function and an amino acid/dipeptide/tripeptide spacer, are used in the prevention and treatment of diabetic retinopathy.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: September 13, 2005
    Assignee: University of Florida
    Inventors: Nicholas Stephen Bodor, Maria Bartolomeo Grant