Abstract: This invention provides compositions and methods for detecting Neisseria gonorrhoeae in a sample. This invention also provides related reaction mixtures, kits, systems, and computers.
Abstract: Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
Abstract: Subject of the present invention is to provide an apparatus, an instrument, and a method particularly useful in multiplex PCR applications permitting short sample measuring times of many samples combined with high sensitivity.
Abstract: The invention provides methods of producing blocked oligonucleotides that include 2?-terminator nucleotides. These blocked oligonucleotides are used primers and probes in a variety of nucleic acid technologies. Related kits are also provided.
Type:
Grant
Filed:
October 18, 2006
Date of Patent:
April 19, 2011
Assignee:
Roche Molecular Systems, Inc
Inventors:
Veeraiah Bodepudi, Amar P. Gupta, Stephen G. Will
Abstract: This invention provides oligonucleotides, reagents and amplification methods for detecting the severe acute respiratory syndrome coronavirus (SARS CoV). This invention also provides related compositions, kits, systems, and computers.
Type:
Grant
Filed:
April 21, 2004
Date of Patent:
May 5, 2009
Assignee:
Genome Institute of Singapore
Inventors:
Ee Chee Ren, Martin L. Hibberd, Lisa Fong Poh Ng
Abstract: This invention provides compositions and methods for detecting Neisseria gonorrhoeae in a sample. This invention also provides related reaction mixtures, kits, systems, and computers.
Abstract: The invention relates to detectable labels useful for detection of nucleotide sequences. Specifically, the invention relates to labeled-imidazole-PEG compounds, such as nucleosides, nucleotides, and nucleic acids incorporating such compounds, and methods utilizing such compounds. The invention further relates to kits comprising labeled imidazole-PEG compounds.
Type:
Grant
Filed:
April 30, 2007
Date of Patent:
November 18, 2008
Assignee:
Roche Molecular Systems, Inc.
Inventors:
Veeraiah Bodepudi, Amar Gupta, Stephen G. Will
Abstract: A reference device for evaluating the performance of a confocal laser scan microscope. The reference device comprises a substrate (53) and reference fluorescing matter distributed over a surface of the substrate (53). The reference fluorescing matter has a predetermined spatial distribution over the latter surface.
Type:
Grant
Filed:
June 5, 2001
Date of Patent:
May 30, 2006
Assignee:
Roche Molecular Systems, Inc.
Inventors:
Karl Anton Josef Schmid, Urban Georg Schnell