Abstract: This invention provides compositions and methods for detecting Neisseria gonorrhoeae in a sample. This invention also provides related reaction mixtures, kits, systems, and computers.
Abstract: The present invention is directed to a method for analyzing the presence of a bacterial pathogen in a clinical sample comprising the steps of (i) at least partially isolating nucleic acid from said sample, characterized in that said nucleic acid is selected from a group consisting of either total nucleic acid, total DNA or total RNA, (ii) quantifying the amount of nucleic acid comprising a preselected sequence which is specific for said bacterial pathogen, and (iii) determining whether said amount of nucleic acid comprising a preselected sequence which is specific for said bacterial pathogen exceeds a first predetermined cut off value.
Type:
Grant
Filed:
December 5, 2003
Date of Patent:
May 18, 2010
Assignees:
Roche Molecular Systems, Inc., The Board of Trustees of the Leland Stanford Junior University
Inventors:
Ellen J. Baron, Wolf-Dieter Engel, Gerd Haberhausen, Peter Kaspar, Andreas M. Kogelnik
Abstract: A purified human papillomavirus gene selected from the group consisting of E1, E6-E7, L1, and L2, wherein said human papillomavirus is selected from the group consisting of HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4. Polypeptides encoded by these genes. The polypeptides can be used in immunogenic compositions.
Type:
Grant
Filed:
November 15, 2001
Date of Patent:
December 7, 2004
Assignee:
Roche Molecular Systems, Inc.
Inventors:
Gerard Orth, Sylvie Beaudenon, Michel Favre, Dina Kremsdorf, Odile Croissant, Gerard Pehau-Arnaudet