Abstract: New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a histidine in position 17. The position 17 histidine is omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.
Type:
Grant
Filed:
May 23, 1988
Date of Patent:
March 19, 1991
Assignee:
Rhone-Poulenc Rorer Pharmaceuticals Inc.
Inventors:
Ronald C. Orlowski, Robert L. Colescott