Abstract: A method of treating hyperproliferative skin disease with substituted quinoline, [1,5]- and [1,8]- naphthyridine and pyrido[2,3-b]pyrazine derivatives is disclosed. The compounds are also anti-allergic, anti-inflammatory and cytoprotective agents. Methods for their preparation and use are disclosed.

Abstract: Certain pyrimidine derivatives are useful in treating allergic, inflammatory and hyperproliferative skin diseases and in suppressing the immune response. Methods for preparing the compounds and methods for their use are also described.

Abstract: A device for iontophoretic delivery of active ingredient to a patient, that includes an electrode, a first cavity for holding a solution of at least partially active ingredient in ionizing form to be delivered to a patient, a member for maintaining a solution in the first cavity while allowing passage of active ingredient from the first cavity, and an ion exchange member separating the electrode and the first cavity for inhibiting the flow of ions having a charge similar to the charge of the ionized form of the active ingredient from the electrode means to the first cavity is disclosed. A method for iontophoretic delivery of active ingredients to a patient is also disclosed.

Abstract: Sustained release dosage forms are made of saponified starch-acrylonitrile graft copolymers and an active ingredient.

Abstract: A method for the topical treatment of hyperproliferative skin diseases in a human is described.Compounds and compositions for use in this method are also described.

Abstract: A method and composition for suppressing the immune response are disclosed which employ an immunosuppressing effective amount of certain tricyclic naphthyridine or pyrido-pyrazine derivatives.

Abstract: Zwitterionic bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed.

Abstract: Substituted quinoline, [1,5]- and [1,8]-naphthyridine and pyrido [2,3-b]pyrazine derivatives are useful positive inotropic agents.

Abstract: Substituted quinoline, [1,5]- and [1,8]-naphthyridine and pyrido[2,3-b]pyrazine derivatives are anti-allergic, anti-inflammatory and cytoprotective agents. Methods for their preparation and use are disclosed.

Abstract: Disclosed are 7- and/or 8-(halo or trifluoromethyl)-substituted-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5 ,6]cyclohepta[1,2-b]pyridines and the pharmaceutically acceptable salts thereof, which possess antihistaminic properties with substantially no sedative properties. Methods for preparing and using the compounds and salts are described.