Patents Represented by Attorney, Agent or Law Firm Richard R. Ryan
  • NPY antagonists: spiroisoquinolinone derivatives
    Patent number: 6348472
    Abstract: A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula I. As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: February 19, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Graham S. Poindexter, Ildiko Antal, Leah M. Giupponi, Robert H. Stoffel, Marc A. Bruce