Abstract: A novel transdermal delivery system for nicotine to satisfy addicted smokers' cravings therefore is comprised of a nicotine base, an acrylate polymer adhesive, a stabilizer and a polyester film backing. The nicotine is absorbed through the skin at sufficiently high levels to reduce or eliminate the desire to smoke, yet its concentration within the acrylate matrix is such that a laminar patch is constructed that is neither bulky nor obvious when worn. A method of manufacture of the transdermal system is also described.

Abstract: The present invention pertains to a method for preparing pulverized Polydextrose having a particle size of under about 125 microns in diameter from Polydextrose which is substantially free of low molecular weight organic acids which comprises the steps of (a) admixing Polydextrose which is substantially free of low molecular weight organic acids with an anti-caking agent to form a mixture, and (b) pulverizing the mixture to form the pulverized Polydextrose. The pulverized Polydextrose composition may be used in a variety of chewing gum products and edible products. The present invention also pertains to methods for preparing the chewing gum and edible products in which the novel composition may be used.

Abstract: Semi-enteric controlled release formulations are comprised of a biological active agent such as an antibiotic that is blended with a water-soluble bulking agent, the mix then coated onto an inert core. The coated active core is further coated with a mixture comprised of an acrylic copolymer, bulking agent and pH dependent food acid. These different coating components possess different solubility characteristics which result in a gradual release of the active in both the stomach and small intestine that provides an increased bioavailability of the active drug.

Abstract: A segmented guard bar and skin flow control members disposed in the spaces between the guard bar segments. Though not limited to any specific type of razor, the present invention is particularly suited for use with a flexible safety razor having a cap member at least one and preferably two blades separated by a spacer, and a blade seat having a plurality of blade support portions separated by corrugations and a segmented guard bar with each segment independently connected to the blade support portions.

Abstract: A razor mechanism particularly suited for use with a flexible cartridge having at least one attachment member moveable in a direction substantially perpendicular to the longitudinal axis of the razor mechanism in response to the flexing of the razor cartridge during shaving.

Abstract: The present invention pertains to semi-enteric drug delivery systems which comprise (a) an inert core, (b) a first coating layer over the core comprising a medicament, and (c) a second coating layer over the first coating layer comprising a mixture of methacrylic acid copolymer, type C, and povidone present in a ratio by weight of from about 2:1 to about 24:1, respectively.

Abstract: A razor mechanism particularly suited for use with a flexible cartridge having at least one attachment member moveable in a direction toward the longitudinal axis of the razor mechanism in response to the flexing of the razor cartridge during shaving and a cartridge support disposed in contact with the cartridge for assisting the cartridge in returning to a substantially linear configuration.

Abstract: A misuse-resistive dosage form for the transdermal delivery of opioid comprises, in combination, 1) one or more opioid permeable to the skin, 2) delivery means permeable to said opioid, 3) one or more antagonist for said opioid releasable upon ingestion or solvent immersion, and 4) impermeable barrier means separating said opioid and said antagonist.

Abstract: The present invention is a wet-shaving unit and a process for making same by injection molding. The present invention is adaptable for addition to conventional razor blade manufacturing methods and existing manufacturing apparatus and facilities. Moreover, the present process results in a product which significantly reduces or eliminates entirely undesirable blade distortion and vibration.

Abstract: A shaving razor has a blade provided with a sputtered hard coating of the boron carbide and with a fluoropolymer lubricant coating overlying the boron carbide coating and adhering directly thereto. The razor provides good durability and good shave performance.

Abstract: An apparatus for making center-filled chewing gum, in which product having up to at least 35-40% by weight of center fill can be produced. The apparatus includes a novel extruder barrel and nozzle arrangement (11) which extrudes a tubular rope of gum (G) through an annular orifice (30), and at the same time supplies a center-fill material (F) to the hollow interior (V) of the tubular rope through a central nozzle (20,21) concentric with the orifice. The center-fill material is fed into the hollow interior of the gum rope at a rate sufficient to just fill the void produced in the gum rope as it is extruded through the nozzle, and without exerting a compressive pressure thereon. With this apparatus, center-filled chewing gum can be produced with up to at least 35-40% by weight of center-fill material and at the same time uniform wall thickness and consistency for the center-filled product can be maintained.

Abstract: The present inventive composition concerns a composite delivery system having a substantially hydrophobic exterior comprising:(a) an agglomerated mixture of a core material selected from the group consisting of sweeteners, flavoring agents and mixtures thereof and a matrix wherein the matrix comprises:(i) about 0.5% to about 20% fat soluble lecithin;(ii) about 65% to about 90% of an edible material having a melting point in the range of about 25.degree. C. to about 100.degree. C. selected from the group consisting of (a) a fatty acid having an iodine value of about 1 to about 10; (b) natural waxes; (c) synthetic waxes; and (d) mixtures thereof,(b) about 0.5% to about 20% of a glyceride; and(c) a silicone based anti-foaming agent in a concentration of about 0.001% to about 0.5%; said composite having a melting point in the range of about 20.degree. C. to about 90.degree. C.

Abstract: A reclosable package for holding items comprises a container having a front portion, top end portion and back portion. An adhesive front label is applied to the front portion of the container. A flexible adhesive flap is then applied which covers the label, top end, and back portions of the container. The label and front portion of the container has a contoured edge formed therein to define an opening edge. The flap includes a non-adhesive pull tab. Lifting the pull tab detaches the front portion along the contoured edge and also removes the top end to open the package. The back of the flap remains attached to the back of the package to form a hinged connection. The flap is resealable to the front portion of the package, to allow the package to be reclosed.