Patents Represented by Attorney Rita Downard Vacca
  • Patent number: 5403576
    Abstract: Hybrid agents for enhancing in vivo diagnostic imaging of body organs and tissues, and methods of preparing and using the same.
    Type: Grant
    Filed: February 4, 1994
    Date of Patent: April 4, 1995
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Youlin Lin, Muthanadar P. Periasamy, Donald R. VanDeripe, William P. Cacheris
  • Patent number: 5396003
    Abstract: A process for the recovery and purification of 1,1,2-trichloroethane from the intermediates produced for the production of ioversol for reuse thereof.
    Type: Grant
    Filed: May 27, 1993
    Date of Patent: March 7, 1995
    Assignee: Mallinckrodt Medical PMC
    Inventor: William Z. McCarthy
  • Patent number: 5371278
    Abstract: The use of a minimal excess of acetoxyacetylchloride as a reagent in the synthesis of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxy-ethyl)glycolamido-2,4,6-triio doisophthalamide.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: December 6, 1994
    Assignee: Mallinckrodt Medical PMC
    Inventors: William Z. McCarthy, Mills T. Kneller, Youlin Lin, Rebecca A. Wallace, David H. White
  • Patent number: 5356520
    Abstract: A process for the separation of amyl acetate, a high boiling point solvent from various high boiling point corrosive impurities, namely, bromoethyl acetate, in an industrial setting to allow for reuse through continuous recycling thereof.
    Type: Grant
    Filed: February 26, 1993
    Date of Patent: October 18, 1994
    Assignee: Mallinckrodt Medical PMC
    Inventors: William Z. McCarthy, Michael J. Gentilcore
  • Patent number: 5356613
    Abstract: The compound N-(2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl)-glycolamido]-N'-methyl-2,4,6 -triiodoisophthalamide and similar such compounds may be used as x-ray contrast agents which are water-soluble, safe and in an aqueous solution are non-viscous. Methods of preparing N-(2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl)-glycolamido]-N'-methyl-2,4,6 -triiodoisophthalamide and the analogous compounds are provided.
    Type: Grant
    Filed: May 8, 1992
    Date of Patent: October 18, 1994
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Youlin Lin, Rebecca A. Wallace, David H. White
  • Patent number: 5324503
    Abstract: Hybrid agents for enhancing in vivo diagnostic imaging of body organs and tissues, and methods of preparing and using the same.
    Type: Grant
    Filed: February 6, 1992
    Date of Patent: June 28, 1994
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Youlin Lin, Muthanadar P. Periasamy, Donald R. VanDeripe
  • Patent number: 5270685
    Abstract: A pressure monitoring device for indicating to the administrator of an injection to a patient that an excess of force has been exerted on the plunger and thereby the fluids contained within the syringe.
    Type: Grant
    Filed: July 2, 1991
    Date of Patent: December 14, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Ronald W. Hagen, Duane L. Horton
  • Patent number: 5261546
    Abstract: The invention relates to a substantially transparent container for liquids on one side of which are opaque light and opaque dark areas of color observable through the container for evaluating contained liquid for particulate impurities. The container is particularly useful for pharmaceutical liquids.
    Type: Grant
    Filed: July 15, 1991
    Date of Patent: November 16, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: Johannes F. Van Der Grift
  • Patent number: 5256393
    Abstract: The use of azeotropic distillation to dry 5-amino-N,N'bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, an intermediate in the production of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxyethyl)glycolamido-2,4,6-triiod oisophthalamide.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: October 26, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: William Z. McCarthy, Mills T. Kneller, Youlin Lin, David H. White
  • Patent number: 5227139
    Abstract: A sanitary sampling system for attachment to a tube portion of a fluid containing enclosure. The sanitary sampling system is comprised of a rigid stem portion for attachment to the tube portion of the fluid enclosure, a stopper portion having a lower portion for insertion into the rigid stem portion and tube portion, a disk-shaped orifice plate fitting for placement on the upper surface of the stopper portion and an adjustable clamp for adjustment around the stem portion, orifice plate fitting and stopper portions of the sanitary sampling system. The sanitary sampling system is designed to enable the stem portion, stopper portion and orifice plate fitting to interlock to form an air-tight and leak-free seal when the adjustable clamp is tightened.
    Type: Grant
    Filed: July 1, 1991
    Date of Patent: July 13, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: David M. Wong